https://scholars.lib.ntu.edu.tw/handle/123456789/157343
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 護理學系 | en |
dc.contributor.author | Lengacher, C. A. | en |
dc.contributor.author | Bennett, M. P. | en |
dc.contributor.author | Gonzalez, L. | en |
dc.contributor.author | Gilvary, D. | en |
dc.contributor.author | Cox, C. E. | en |
dc.contributor.author | Cantor, A. | en |
dc.contributor.author | Jacobsen, P. B. | en |
dc.contributor.author | Yang, C. | en |
dc.contributor.author | Djeu, J. | en |
dc.creator | 楊秋月 | zh-tw |
dc.creator | Lengacher, C. A.; Bennett, M. P.; Gonzalez, L.; Gilvary, D.; Cox, C. E.; Cantor, A.; Jacobsen, P. B.; Yang, C.; Djeu, J. | en |
dc.date | 2008 | en |
dc.date.accessioned | 2009-12-18T01:07:15Z | - |
dc.date.accessioned | 2018-07-07T01:48:51Z | - |
dc.date.available | 2009-12-18T01:07:15Z | - |
dc.date.available | 2018-07-07T01:48:51Z | - |
dc.date.issued | 2008 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/174507 | - |
dc.description.abstract | Background: The use of relaxation and guided imagery to reduce stress and improve immune function has great potential benefits for patients with breast cancer. Methods: This pilot study used a pretest-posttest experimental design with 28 breast cancer patients, aged 25 to 75 years, with the diagnosis of stage 0, 1, or 2 breast cancer. The experimental group received a relaxation and guided imagery intervention and the control group received standard care. The effects of the intervention on immune function were measured by natural killer (NK) cell cytotoxicity and IL-2- activated NK cell activity prior to surgery and 4 weeks postsurgery . NK cell activity was measured using a 15-hr incubation chromium release assay. Cytotoxicity of NK cells was measured against chromium-labeled K- 562 target cells. IL -2 was used to enhance reactivity of NK cells against tumor cells. After incubation for 15 hr, cytotoxicity was measured through the release of radioactive chromium. Results: Significant differences between groups were found at 4 weeks postsurgery, T-tests showed increased NK cell cytotoxicity for the intervention group at 100:1, 50:1, and 25:1 effector cell: target cell ratios (E:T) (p <.01 to p <.05) and increased activation for IL-2 at 100:1, 50:1,25:1,and 12.5:1 (E:T) (p <.01 to p <.05) for the intervention group as compared to the control group. Discussion: These findings suggest that a relaxation intervention such as guided imagery could have an effect on NK cell cytotoxicity and NK cell cytotoxicity after activation with IL-2 in patients undergoing surgery for breast cancer. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | BIOLOGICAL RESEARCH FOR NURSING v.9 n.3 pp.205-214 | en |
dc.relation.ispartof | Biological Research for Nursing | en_US |
dc.subject | guided imagery | en |
dc.subject | immune response | en |
dc.subject | breast cancer | en |
dc.subject | natural killer cells | en |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | interleukin 2; adult; aged; article; breast tumor; female; human; immunology; middle aged; natural killer cell; psychological aspect; psychotherapy; Adult; Aged; Breast Neoplasms; Female; Humans; Imagery (Psychotherapy); Interleukin-2; Killer Cells, Natural; Middle Aged | - |
dc.title | Immune Responses to Guided Imagery during Breast Cancer Treatment | en |
dc.identifier.doi | 10.1177/1099800407309374 | - |
dc.relation.pages | 205-214 | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en_US | - |
顯示於: | 護理學系所 |
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