Effects of individualized exercise training on arterial function, walking ability and quality of life in patients with peripheral arterial disease post surgery
Date Issued
2007
Date
2007
Author(s)
Tsai, Chung-Hsien
DOI
zh-TW
Abstract
Background and purpose: Fewer studies investigated the exercise training effects on patients with peripheral arterial disease (PAD) after vascular intervention. The purposes of this study were to investigate individualized exercise training effects on arterial function, walking ability and quality of life (QoL), and correlations among changes of all variables in these patients. Methods: Thirty-two symptomatic post-vascular intervention subjects were recruited and randomly assigned into control group and exercise group whom received 12-week individualized exercise program. All subjects were asked to maintain their life style, diet, and medicine during study period and had arterial function, walking ability (including grades of Walking Impairment Questionnaire (WIQ)), and Vascular Quality of Life questionnaire (VascuQoL) measured at baseline and 12 weeks after. Twelve subjects in exercise group and 13 in control group completed the study. Independent t-test and Chi-square test were performed to compare the baseline data between groups. A 2 × 2 two-way mixed ANOVA model was performed to compare the between- and within-group differences in all variables. Mean arterial pressure was used as the covariate in analyzing the effects on variables of arterial function. Pearson correlation analysis was used to investigate the correlations among the changes in arterial function, walking ability and QoL. Results: There were no significant differences in baseline data between groups except diastolic blood pressure. Significant interactions were noted in variables of reflection index (RI) of more affected side, toe fluxs of two sides, initial claudication and maximal walking time, stairs grades of WIQ, acivity and symptom and sum grades of VascuQoL. Post-hocs showed significant within-control-group change in RI of more affected side, within-exercise-group changes in other variables with significant interaction, and between-group post-test differences in toe flux of more affected side and acivity grades of VascuQoL. Other variables with significant interaction showed no between-group post-test differences. For those without significant interactions, symptom and speed grades of WIQ and emotion grades of VascuQoL showed only significant within-group main differences. For correlations, positive relationships were noted between changes of toe flux and walking ability, toe pressure and walking ability, as well as walking ability and QoL. Negative relationship was noted between changes of brachial-ankle pulse wave velocity and walking ability. Conclusion: Individualized exercise training could significantly improve toe fluxs, walking time and ability of up/down stairs, as well as activity- and symptom-associated QoL in PAD patients post-vascular intervention.
Subjects
周邊動脈疾病術後
血管功能
行走能力
生活品質
個別化運動訓練
Peripheral arterial disease post vascular intervention
Arterial function
Walking ability
Quality of life
Individualized exercise training
Type
other
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