Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. Physical Therapy / 物理治療學系所
  4. Effects of Task-Oriented Circuit Training on Lower Extremity Motor Function and Brain Plasticity in Patients with Sub-acute Stroke: Meta-analysis and Preliminary Study
 
  • Details

Effects of Task-Oriented Circuit Training on Lower Extremity Motor Function and Brain Plasticity in Patients with Sub-acute Stroke: Meta-analysis and Preliminary Study

Date Issued
2012
Date
2012
Author(s)
Wong, Connie
URI
http://ntur.lib.ntu.edu.tw//handle/246246/250511
Abstract
Recent studies have shown that task-oriented circuit training is effective in improving walking speed and walking endurance in patients with chronic stroke. However, the training effects of task-oriented approach in patients with sub-acute stroke remain unclear. It also remains to be explored regarding whether task-oriented training has effects on structural integrity of the corticospinal tract (CST) and activation patterns of the sensorimotor cortex (SMC) during ankle movements in patients with sub-acute stroke. Therefore, the purposes of this study were: (1) to investigate the effects of task-oriented training on lower extremity motor functions in patients with sub-acute stroke using meta-analysis; (2) to preliminarily investigate the effects of a 4-week task-oriented circuit training program on lower extremity motor functions (primary outcomes), the structural integrity of the CST of lower extremity motor fibers and brain activation patterns of the SMC (secondary outcomes) in patients with sub-acute stroke. We conducted a meta-analysis to examine the effects of task-oriented approach in patients with sub-acute stroke and a preliminary study of an assessor-blind randomized controlled trial with a total of 3 patients with sub-acute stroke (experimental group: E1; control group: C1 and C2). The participants were randomly assigned to the experimental group or the control group. All participants received 4 weeks of exercise training, which were 4 sessions per week and 60 minutes for each session. The experimental group received task-oriented circuit training to improve lower extremity motor functions. The control group received stretch exercises and upper extremity activities in sitting posture. Both groups received clinical asessments on lower extremity motor functions (primary outcomes), the structural integrity of the CST using diffusion spectrum imaging, and the cortical activation patterns of the SMC using functional magnetic resonance imaging(secondary outcomes) at baseline, post-training (week 4), and 1 month follow-up (week 8). Because of the small number of subjects, we also included one subject (E2) who received the same training programs as experimental group in our pilot study as one subject of the training group result. Training effects were descriptively analyzed for individual subjects. The meta-analysis results showed that task-oriented training led to significantly greater improvement than other training on 6-minute walking distance (mean difference = 82.49 meter; 95% confidence interval: 27.59-137.38) and comfortable gait speed (standardized mean difference = 0.27; 95% confidence interval: 0.03-0.52) in patients with subacute stroke. Our preliminary results showed that the experimental group achieved meaningful improvements in most of the primary outcomes but not for the control group. In addition, different brain reorganization patterns were observed in the two groups. The results of meta-analysis provide relevant clinical evidence for the effects of task-oriented training on lower extremity motor functions, and this preliminary study provides the pilot result for the effects of task-oriented circuit training on lower extremity motor functions, brain structural and functional plasticity in patients with sub-acute stroke.
Subjects
stroke
task-oriented circuit training
walking function
corticospinal tract
brain plasticity
Type
thesis
File(s)
Loading...
Thumbnail Image
Name

ntu-101-R99428014-1.pdf

Size

23.32 KB

Format

Adobe PDF

Checksum

(MD5):cd72c118cea9f3c0bce3b213a99fa9ac

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science