|Title:||The suppressive effect of electrical stimulation on nociceptive responses in the rat||Authors:||WANG, SHWU-FEN
|Issue Date:||1997||Journal Volume:||v.77||Journal Issue:||n.8||Start page/Pages:||839-847||Source:||PHYSICAL THERAPY||Abstract:||
Background and Purpose: The aim of this investigation was to study the effect of electrical stimulation on nociceptive responses within the lumbar levels of the rat spinal cord. Methods: A single high-energy thermal pulse produced by a surgical laser stimulator (5W, 30 milliseconds ) was applied on the plantar surface of the hind paws of male Sprague- Dawley rats. The spinal cord field potential evoked by the laser pulse was used as an indicator of thermosensitive nociceptive responses. Low- intensity single stimulation, high-intensity single stimulation, low- intensity train stimulation, and high-intensity train stimulation were applied on the common peroneal nerve with protected cuff electrodes in different trials. Results: Neither low- intensity nor high- intensity single stimulation suppressed field potentials. Furthermore, high- intensity train stimulation elicited biphasic inhibition at a wider range of intervals lasting for 20 seconds. Conclusion and Discussion : The results demonstrate that two models of train electrical stimulation can produce two patterns of fast- onset (within milliseconds), short-duration (within 20 seconds) inhibition of field potentials in the spinal cord. These results provide evidence that noxious heat-related impulses are modulated by the presence of specific electrical stimulation. The clinical application of transcutaneous electrical nerve stimulation to block pain is supported.
|Appears in Collections:||物理治療學系所|
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