The Predictive Model of Quality of Life for Systemic Lupus Erythematosus – A Path Analysis
Date Issued
2015
Date
2015
Author(s)
Wu, Chao-Yi
Abstract
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease with unknown etiology. Within these 40 years, along with the progress of diagnosis, the mortality rate declined. However, the uncertainty of disease causes physical discomfort and mental health distress. Quality of life (QOL) describes how a person interprets its life satisfaction. Fatigue, pain, and depression symptoms are mentioned to be predictors of QOL in patients with SLE. Although many researchers want to find out the mechanism how symptoms lead to QOL. However, result is still unclear. Thus, the purpose of our study is to apply path analysis to verity our predictive QOL models. Methods: There were 94 participants in our study. Participants were recruited from an outpatient clinic of National Taiwan University Hospital and met the following criteria: (1) confirmed SLE diagnosis based on ACR; (2) aged above 20; (3) reached education level above 5th grade of elementary school; (4) reached a minimum score of 24 on MMSE; (5) stably followed up in clinics. Participant evaluated disease activity (SLEDAI-2000) by clinician. Patients evaluated fatigue (FACIT-F), pain (Pain-NRS), depression (BDI-II), anxiety (BAI), sense of competence (OSA-myself), environmental impact (OSA-environment), sense of mastery (Mastery scale), and QOL (WHOQOL-BREF-TW). We applied SPSS 19 and LISREL 8.51 to conduct data analysis. Results: The finding of study found sense of competence a critical predictor of QOL, and fatigue, pain, depression, and anxiety all indirectly influence QOL via sense of competence. Fatigue, depression, sense of competence, and environmental impact are the most influential predictors in physical health, psychological health, social relationships, and environmental domains of QOL. Conclusion: We hope by the confirmation of the predictive model of the study would provide directions for clinicians to derive strategies aiming at improving QOL for patients with SLE.
Subjects
Occupational Therapy
SLE
quality of life
path analysis
SDGs
Type
thesis
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