Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Bioresources and Agriculture / 生物資源暨農學院
  3. School of Veterinary Medicine / 獸醫專業學院
  4. Veterinary Medicine / 獸醫學系
  5. Viral Nucleic Acid Diagnostic Assays for Canine Infectious Respiratory Disease and Analysis of Clinical Cases
 
  • Details

Viral Nucleic Acid Diagnostic Assays for Canine Infectious Respiratory Disease and Analysis of Clinical Cases

Date Issued
2006
Date
2006
Author(s)
Huang, Chiung-Yi
DOI
zh-TW
URI
http://ntur.lib.ntu.edu.tw//handle/246246/59966
Abstract
Canine infectious respiratory disease (CIRD) is a general call of respiratory infections in dogs. Several studies of natural outbreaks of the disease have shown that the etiology is complex, with a variety of viruses and bacteria involved. The viruses that have been most frequently reported to be present are canine distemper virus (CDV), canine adenovirus type 1 and type 2 (CAV-1 and CAV-2), canine herpesvirus (CHV), canine parainfluenza virus type 2 (CPIV-2), and canine respiratory coronavirus (CRCoV). We detected these viruses from clinical samples of 54 cases with specific nucleic acid diagnostic assays based on RT-nPCR / n-PCR, and obtained the detection rates as follows: CDV: 41 %; CAV-2: 28 %; CPIV-2: 13 %; CRCoV: 8 %; CHV: 4 %. A population of dogs (26%) had evidence of infections with several viruses at the same time. The coinfection patterns are: CDV with CPIV-2 (9 %), CDV with CAV-2 (7 %), CAV-2 with CPIV-2 (4 %), and CDV with CHV (2 %). The infectious patterns involved with three viruses including: CAV-2, CHV and CRCoV (2 %); CDV, CAV-2 and CRCoV (2 %). Generally speaking, detection rates of nasal swab, oral swab and conjunctival swab have a elevation compared with whole blood. The gene sequence results of the RT-nPCR and n-PCR products of representative positive samples showed 98.7 – 100% nucleotide identity with corresponding viral gene and 95 – 100% with foreign strains. The nucleotides variation in CRCoV, CPIV-2, and CHV can be differentiated local strains form foreign strains. According to the statistical analysis results, any infectious pattern of these virus showed a significant variability with the severity of upper respiratory symptoms (P < 0.01), and higher variability in secondary bacterial infections (P < 0.01). In some particular viral infections showed a significant variability with the clinical sign of vomiting and diarrhea (P < 0.05)
Subjects
犬傳染性呼吸道疾病
canine infectious respiratory disease
SDGs

[SDGs]SDG3

Type
thesis
File(s)
Loading...
Thumbnail Image
Name

ntu-95-R93629004-1.pdf

Size

23.31 KB

Format

Adobe PDF

Checksum

(MD5):521ad34c7037660c32b9caa2ce3f3572

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science