https://scholars.lib.ntu.edu.tw/handle/123456789/177230
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 邱勝賢 | en |
dc.contributor | 臺灣大學:化學研究所 | zh_TW |
dc.contributor.author | 洪偉崇 | zh |
dc.contributor.author | Hung, Wei-Chung | en |
dc.creator | 洪偉崇 | zh |
dc.creator | Hung, Wei-Chung | en |
dc.date | 2005 | en |
dc.date.accessioned | 2007-11-26T02:17:58Z | - |
dc.date.accessioned | 2018-07-10T05:02:41Z | - |
dc.date.available | 2007-11-26T02:17:58Z | - |
dc.date.available | 2018-07-10T05:02:41Z | - |
dc.date.issued | 2005 | - |
dc.identifier | zh-TW | en |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/51639 | - |
dc.description.abstract | 我們發現benzylic azides與trialkyl phosphite作用形成dialkyl phosphoramidate的反應,可相當有效率地被應用於不同孔徑的大環分子與dibenzylammonium ion (DBA+) 之辨識系統,來合成[2]車輪烷分子。若以二十四員環之dibenzo-[24]crown-8 (DB24C8),或是與DBA+之錯合能力相當弱的di(p-toluidine)[24]crown-8 (DPT24C8),則diethyl phosphoramidate可作為適當之封鎖基;若大環分子為二十六員環,則須以dibutyl phosphoramidate作為封鎖基。 我們亦合成一個具有雙重辨識單元的大環分子,不但可與DBA+錯合,更可利用鈀(II)離子之四配位特性,連接大環分子與吡啶衍生物,以形成準車輪烷的結構。我們分別利用這兩種辨識單元,合成出對應的[2]車輪烷分子。 | en |
dc.description.abstract | The mild and efficient reaction between trialkyl phosphite and benzylic azides allows us to construct rotaxanes utilizing the recognition motif of macrocycles, with different sizes, and dibenzylammonium ion (DBA+). In the case of 24-membered macrocycles, such as dibenzo[24]crown-8 (DB24C8) and di(p-toluidine)[24]crown-8, which binds DBA+ ions much more weakly than does DB24C8, diethyl phosphoramidate is a suitable stopper. For 26-membered macrocycle, the larger dibutyl phosphoramidate is needed to act as a stopper. The dual-use macrocycle, which owns double recognition motif was also synthesized. Not only complexing with DBA+, it also attached with the derivatives of pyridine via Pd(II). Applying both recognition motifs, rotaxanes are successfully synthesized respectively. | en |
dc.description.tableofcontents | 摘 要:I 目 錄:III 論文發表:V 式 子:VI 圖 表:VII 表 格:IX 壹、緒 論:1 1.1 內鎖型分子:車輪烷及環連體:1 1.2 冠醚(crown ether)與二級銨離子之辨識系統:6 貳、結果與討論:13 2.1 研究動機:13 2.2 桿狀分子的合成:16 2.3 以Diethyl Phosphoramidate為封鎖基—以冠醚分子為大環:18 2.4 以Diethyl Phosphoramidate為封鎖基—於新的大環系統:26 2.5 以Dibutyl Phosphoramidate為封鎖基—於雙用大環分子:30 2.6 應用雙用大環分子之配基接受體辨識單元合成車輪烷:36 參、結論:38 肆、實驗部分:40 伍、參考文獻:52 附 錄:1H與13C核磁共振光譜及結合常數測量:55 | zh_TW |
dc.language | zh-TW | en |
dc.language.iso | en_US | - |
dc.subject | 超分子化學 | en |
dc.subject | 車輪烷 | en |
dc.subject | supramolecular chemistry | en |
dc.subject | rotaxane | en |
dc.title | 合成車輪烷的新方法及其應用 | zh |
dc.title | The Mild and Efficient Method of Rotaxane Syntheses and Its Applications | en |
dc.type | thesis | en |
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J.; Chrystal, E. J. T.; Glink, P. T.; Menzer, S.; Philp, D.; Spencer, N.; Stoddart, J. F.; Tasker, P. A.; Williams D. J. Angew. Chem. Int. Ed. Engl. 1995, 34, 1869–1871. 33.Cheng, P. N.; Hung, W. C.; Chiu, S. H. Tetrahedron Lett. 2005, 46, 4239-4242. 34.Moriuchi, T.; Bandoh, S.; Kamikawa, M.; Hirao, T. Chem. Lett. 2000, 148-149 35.Snowden, T. S.; Bisson, A. P.; Anslyn, E. V. J. Am. Chem. Soc. 1999, 121, 6324-6325 36.Binding Constant; Connors, K. A., Ed.; John Wiley & Sons: New York, 1999. 37.Furusho, Y.; Matsuyama, T.; Takata, T.; Moriuchib, T.; Hirao, T. Tetrahedron Lett. 2004, 45, 9593–9597 | en |
item.languageiso639-1 | en_US | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.openairetype | thesis | - |
item.openairecristype | http://purl.org/coar/resource_type/c_46ec | - |
item.cerifentitytype | Publications | - |
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