Chapter 10 Genomics

Abstract

The advent of DNA sequencing techniques changed experimental biology, and automation has enhanced the rate of change. 2. Genomics is the development and application of techniques for: a. Mapping chromosomes. b. Sequencing genomes. c. Computational analysis of entire genomes. 3. Subfields of genomics are: a. Structural genomics, the genetic and physical mapping and sequencing of chromosomes. b. Functional genomics, comprehensive analysis of gene functions and of non-gene sequences in entire genomes. c. Comparative genomics, comparison of entire genomes across species, looking at functions and evolutionary relationships. 4. This section focuses on structural genetics, specifically genome sequencing.