Using Microarray Data to Explore Primary and Nonprimary Regulatory Events of Escherichia coli

In recent years, microarray have been widly used to simultaneously monitor expression of a large number of genes and to establish gene regulatory networks.In this study , we use the public-available of E. coli microarray database, to rediscovery the regulation events between the target genes and their downstream targets.We use the coefficient of intrinsic dependence and correlation indentify the genes regulated by modE.We also use the cluster analysis to visualize the possible patterns of expression under different regulatory mechanisms. The results may provide insight into the prediction of gene regulatory mechanisms in the future.