https://scholars.lib.ntu.edu.tw/handle/123456789/187494
標題: | Metabolism of Inorganic Arsenic and Non-Cancerous Health Hazards Associated with Chronic Exposure in Humans | 作者: | TSENG, CHIN-HSIAO | 關鍵字: | inorganic arsenic;human exposure;health hazards;blackfoot disease;neuropathy | 公開日期: | 2007 | 卷: | v.28 | 期: | n.2 | 起(迄)頁: | 349-357 | 來源出版物: | JOURNAL OF ENVIRONMENTAL BIOLOGY | 摘要: | Humans con be exposed to arsenic from a variety of environmental, occupational and medicinal sources. Exposure from drinking water is the most common source nowadays, Inorganic arsenic is metabolized by two main biochemical reactions: reduction and oxidative methylation. Recent studies have confirmed a reactivation of the toxic effects of arsenic associated with such methylation process, because the methylated metabolites, especially the trivalent forms, are more toxic than the inorganic arsenicals. Chronic exposure to arsenic can cause a variety of cancerous and non -cancerous health hazards in humans. The main non-cancerous health hazards include cardiovascular disease, skin lesions, neurological problems, diabetes mellitus and hypertension. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/88336 |
顯示於: | 醫學系 |
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