https://scholars.lib.ntu.edu.tw/handle/123456789/188103
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 內科 | en |
dc.contributor.author | Lau, Chu-Pak | en_US |
dc.contributor.author | Tse, Hung-Fat | en_US |
dc.contributor.author | Yu, Cheuk-Man | en_US |
dc.contributor.author | Teo, Wee-Siong | en_US |
dc.contributor.author | Kam, Ruth | en_US |
dc.contributor.author | Ng, Kheng-Siang | en_US |
dc.contributor.author | Huang, Stephen Shoei K | en_US |
dc.contributor.author | JIUNN-LEE LIN | en_US |
dc.contributor.author | Fitts, Stephanie M | en_US |
dc.contributor.author | Hettrick, Douglas A | en_US |
dc.contributor.author | Hill, Michael R.S | en_US |
dc.creator | 林俊立 | zh-tw |
dc.creator | LIN, JIUNN-LEE | en |
dc.date | 2001 | en |
dc.date.accessioned | 2008-12-29T07:07:06Z | - |
dc.date.accessioned | 2018-07-11T05:22:17Z | - |
dc.date.available | 2008-12-29T07:07:06Z | - |
dc.date.available | 2018-07-11T05:22:17Z | - |
dc.date.issued | 2001 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/95150 | - |
dc.identifier.uri | https://www.scopus.com/record/display.uri?eid=2-s2.0-0035880614&doi=10.1016%2fS0002-9149%2801%2901681-2&origin=inward&txGid=835612fb895ce17edaf1f386f776ac7f | - |
dc.description.abstract | Atrial pacing has been shown to delay the onset of atrial fibrillation ( AF) when compared with ventricular pacing in patients with sick sinus syndrome. The role for pacing in the control of AF in patients without bradycardia is uncertain. We performed a randomized, crossover, single- blinded study in 22 patients (14 women, aged 63 +/- 10 years ) with paroxysmal AF refractory to treatment with oral sotalol (202 +/- 68 mg/day ) and no bradycardic indication for pacing. All patients received a dual- chamber pacemaker with 2 atrial pacing leads positioned at the high right atrium and coronary sinus ostium, respectively. Patients were randomized in a crossover fashion to be paced for 12 weeks, either with high right atrial (RA) pacing at 30 beats /min ("Off") or dual-site RA pacing with an overdrive algorithm that maintained atrial pacing at a rate slightly above the sinus rate ("On"). Treatment on resulted in a significantly higher percentage of atrial pacing and a reduction in atrial ectopic frequency than the treatment off period. The time to the first clinical AF recurrence was prolonged (15 +/- 17 to 50 +/- 35 days, p = 0.006), and total AF burden was reduced (45 +/- 34% vs 22 +/- 29%, p = 0 .04) in the on-treatment phase. However, there was no difference in AF checklist symptom scores or overall quality -of-life measures. Dual-site RA pacing with continued sinus overdrive prolonged the time to AF recurrence and decreased AF burden in patients with paroxysmal AF. The absence of a major impact on symptom control suggests that pacing should be used as an adjunctive therapy with other treatment modalities for AF. (C) 2001 by Excerpta Medica, Inc. | en_US |
dc.language | en-us | en |
dc.language.iso | en_US | en_US |
dc.relation | AMERICAN JOURNAL OF CARDIOLOGY v.88 n.4 pp.371-375 | en |
dc.relation.ispartof | AMERICAN JOURNAL OF CARDIOLOGY | en_US |
dc.subject | QUALITY-OF-LIFE | en_US |
dc.subject | PREVENTION | en_US |
dc.subject | CHAMBER | en_US |
dc.subject | FLUTTER | en_US |
dc.subject | TRIAL | en_US |
dc.title | Dual-Site Atrial Pacing for Atrial Fibrillation in Patients without Bradycardia | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/S0002-9149(01)01681-2 | - |
dc.identifier.pmid | 11545756 | - |
dc.relation.pages | 371 | en_US |
dc.relation.journalvolume | 88 | en_US |
dc.relation.journalissue | 4 | en_US |
dc.relation.pageend | 375 | en_US |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en_US | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0003-2148-3956 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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