Skip navigation
  • 中文
  • English

DSpace CRIS

  • DSpace logo
  • Home
  • Organizations
  • Researchers
  • Research Outputs
  • Explore by
    • Organizations
    • Researchers
    • Research Outputs
  • Academic & Publications
  • Sign in
  • 中文
  • English
  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/188428
Title: Independent Association of Uric Acid Levels with Peripheral Arterial Disease in Taiwanese Patients with Type 2 Diabetes
Authors: TSENG, CHIN-HSIAO
Keywords: peripheral arterial disease;risk factor;Taiwanese;Type 2 diabetes;uric acid
Issue Date: 2004
Journal Volume: v.21
Journal Issue: n.7
Start page/Pages: 724-729
Source: DIABETIC MEDICINE 
Abstract: 
Aims Hyperuricaemia may be a risk factor for atherosclerotic disease. Its association with peripheral arterial disease ( PAD) has not been studied in Taiwanese patients with Type 2 diabetes. Methods Uric acid (UA) levels and PAD were evaluated in 508 Taiwanese outpatients with Type 2 diabetes( 210 men, 298 women; mean age +/- SD, 63.8 +/- 10.6 years). PAD was diagnosed when the ankle-brachial index was < 0.9. Patients with an ankle- brachial index of greater than or equal to 1.3 were excluded because of possible medial arterial calcification. Potential confounding variables with P < 0.10 were adjusted for in multivariate analyses. Results In univariate analyses, UA levels were higher in patients with PAD than in those without PAD (345.0 +/- 95.2 vs. 309.3 +/- 89.2 mumol/l; P < 0.0005). Prevalences of PAD for quintiles of UA levels were 6.8, 8.9, 10.2, 13.1 and 16. 5%, respectively (P-trend < 0.05). With UA level as a continuous variable, the multivariate-adjusted odds ratio ( 95% confidence interval) for PAD was 1.005 (1.001-1.008) (P< 0.01). The optimal cut-off point for UA as determined by the receiver operating characteristic curve was 264.7 mumol/ l. The sensitivity and specificity at this cut-off point was 82.6 and 33.3%, respectively. The area under curve was 0 .60(95% confidence interval: 0.53-0.68). The multivariate- adjusted odds ratio for PAD for UA above this level was 2. 736 (1.239-6.043) (P < 0.05). The results after excluding 56 cases using diuretics were similar. Conclusions Elevated uric acid level is a significant and independent risk factor for PAD in Taiwanese patients with Type 2 diabetes.
URI: http://ntur.lib.ntu.edu.tw//handle/246246/95280
metadata.dc.subject.other: [SDGs]SDG3
Appears in Collections:醫學系

Show full item record

Page view(s)

18
checked on Jun 25, 2022

Google ScholarTM

Check

Related Items in TAIR


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Sherpa Romeo網站查詢,以確認出版單位之版權政策。
    Please use Sherpa Romeo to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)
Build with DSpace-CRIS - Extension maintained and optimized by Logo 4SCIENCE Feedback