|Title:||The Angio-Seal (Tm) Arterial Closure Device for Early Ambulation after Elective Percutaneous Coronary Intervention in Patients Receiving Low-Dose Enoxaparin||Authors:||LAI, YUNG-CHANG
|Keywords:||ENOXAPARIN;UNFRACTIONATED HEPARIN;ANGIO-SEAL (TM);VASCULAR CLOSURE DEVICE;PERCUTANEOUS CORONARY INTERVENTION||Issue Date:||2008||Journal Volume:||36||Journal Issue:||5||Start page/Pages:||1077||Source:||JOURNAL OF INTERNATIONAL MEDICAL RESEARCH||Abstract:||
This study evaluated the efficacy and safety of use of the Angio-Seal vascular closure device deployment for early ambulation (2 h) after elective percutaneous coronary intervention in 143 consecutive patients receiving either intravenous low-dose enoxaparin (0.5 mg/kg) or unfractionated heparin (UFH). The initial success rate of Angio-Seal(trade mark) deployment was 98.6%, with no significant difference between the UFH group (98.9%) and the enoxaparin group (98.0%). In-hospital and clinic outcomes were evaluated in the 141 patients with successful Angio- Seal deployment. During hospitalization, there were no deaths, myocardial infarction, urgent target vessel revascularization or bleeding events in either group; three patients in the UFH group and none in the enoxaparin group had minor vascular complications (differences not significant). In clinic follow-up, two patients in the UFH group and none in the enoxaparin group had major vascular complications (differences not significant). Routine use of the Angio-Seal(trade mark) for early ambulation in patients receiving intravenous low-dose enoxaparin compared with UFH provides promising efficacy and safety for daily practice.
|Appears in Collections:||醫學系|
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