https://scholars.lib.ntu.edu.tw/handle/123456789/189609
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 內科 | en |
dc.contributor.author | Goto, Shinya | en |
dc.contributor.author | Bhatt, Deepak L. | en |
dc.contributor.author | Rother, Joachim | en |
dc.contributor.author | Alberts, Mark | en |
dc.contributor.author | Hill, Michael D. | en |
dc.contributor.author | Ikeda, Yasuo | en |
dc.contributor.author | Uchiyama, Shinichiro | en |
dc.contributor.author | D'Agostino, Ralph | en |
dc.contributor.author | Ohman, E. Magnus | en |
dc.contributor.author | Liau, Chiau-Suong | en |
dc.contributor.author | Hirsch, Alan T. | en |
dc.contributor.author | Mas, Jean-Louis | en |
dc.contributor.author | Wilson, Peter W.F. | en |
dc.contributor.author | Corbalan, Ramon | en |
dc.contributor.author | Aichner, Franz | en |
dc.creator | 廖朝崧 | zh-tw |
dc.creator | Goto, Shinya; Bhatt, Deepak L.; Röther, Joachim; Alberts, Mark; Hill, Michael D.; Ikeda, Yasuo; Uchiyama, Shinichiro; D'Agostino, Ralph; Ohman, E. Magnus; Liau, Chiau-Suong; Hirsch, Alan T.; Mas, Jean-Louis; Wilson, Peter W.F.; Corbalán, Ramón; Aichner, Franz | en |
dc.date | 2008 | en |
dc.date.accessioned | 2009-12-18T02:20:08Z | - |
dc.date.accessioned | 2018-07-11T06:17:05Z | - |
dc.date.available | 2009-12-18T02:20:08Z | - |
dc.date.available | 2018-07-11T06:17:05Z | - |
dc.date.issued | 2008 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/174617 | - |
dc.description.abstract | Background Atrial fibrillation (AF) is a major risk factor ( RF) for ischemic stroke. Its prevalence and prognostic impact in patients with atherothrombosis are unclear. Methods Risk factors, drug usage, and 1-year cardiovascular( CV) outcomes (CV death, myocardial infarction [MI], and stroke) were compared in AF and non-AF patients from the REduction of Atherothrombosis for Continued Health (REACH) Registry, an international, prospective cohort of 68,236 stable outpatients with established otherothrombosis or >= 3 atherothrombotic RFs. Result Atrial fibrillation and 1-year follow-up data are available for 63,589 patients. The prevalence of AF was, 12.5%, 13.7%, 11.5%, and 6.2% among coronary artery disease, CV disease, peripheral artery disease, and RF-only patients, respectively. Of the 6,814 patients with AF, 6.7% experienced CV death, nonfatal MI, or nonfatal stroke within a year. The annual incidence of nonfatal stroke (2.4% vs 1.6%, P < .0001) and unstable angina (6.0% vs 4.0 %, P < .00001) was higher, and CV death was more than double (3.2% vs 1.4% , P < .0001), in AF versus non-AF patients. In these patients with or at high risk of atherothrombosis, most patients with AF received antiplatelet agents, but only 53.1% were treated with oral anticoagulants. Even with high CHADS(2) (congestive heart failure, hypertension, aging, diabetes mellitus, and stroke) scores, anticoagulant use did not exceed (59%). The rate of bleeding requiring hospitalization was higher in AF versus non-AF patients (1.5% vs 0.8%, P < .0001), possibly related to the more frequent use of anticoagulants (53.1% vs 7.1%). Conclusions Atrial fibrillation is common in patients with atherothrombosis, associated with more frequent fatal and nonfatal CV outcomes, and underuse of oral anticoagulants. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | AMERICAN HEART JOURNAL v.156 n.5 pp.855-863 | en |
dc.relation.ispartof | American Heart Journal | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | acetylsalicylic acid; anticoagulant agent; antithrombocytic agent; aged; aging; artery disease; article; atherosclerosis; bleeding; cardiovascular risk; comparative study; congestive heart failure; controlled study; coronary artery disease; diabetes mellitus; drug use; female; follow up; heart atrium fibrillation; heart death; heart infarction; hospitalization; human; hypertension; major clinical study; male; outcome assessment; prevalence; priority journal; prognosis; prospective study; risk factor; stroke; thrombosis; unstable angina pectoris | - |
dc.title | Prevalence, Clinical Profile, and Cardiovascular Outcomes of Atrial Fibrillation Patients with Atherothrombosis | en |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.ahj.2008.06.029 | - |
dc.relation.pages | 855-863.e2 | - |
item.fulltext | no fulltext | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en_US | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
顯示於: | 醫學系 |
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