https://scholars.lib.ntu.edu.tw/handle/123456789/190865
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 臺大醫院-內科部;臺大醫學院-微生物學科暨研究所; | - |
dc.contributor.author | Lin, Yi-Tsung | en_US |
dc.contributor.author | Pan, Yi-Jiun | en_US |
dc.contributor.author | Lin, Tzu-Lung | en_US |
dc.contributor.author | Fung, Chang-Phone | en_US |
dc.contributor.author | JIN-TOWN WANG | en_US |
dc.creator | Lin, Yi-Tsung;Pan, Yi-Jiun;Lin, Tzu-Lung;Fung, Chang-Phone;Wang, Jin-Town | en |
dc.creator | 林稚容;王錦堂 | zh-tw |
dc.date | 2015 | - |
dc.date.accessioned | 2017-02-15T03:41:07Z | - |
dc.date.accessioned | 2018-07-11T07:09:21Z | - |
dc.date.available | 2017-02-15T03:41:07Z | - |
dc.date.available | 2018-07-11T07:09:21Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/270731 | - |
dc.description.abstract | A CMY-2-producing capsular type K2 Klebsiella pneumoniae strain (TVGHKP93) with multidrug resistance was isolated from a recurrent liver abscess in a patient who also carried a CMY-2-producing Escherichia coli strain (TVGHEC01) in the stool. TVGHKP93 retained its high virulence compared with that of the isogenic strain (TVGHKP60) with wild-type resistance from the first liver abscess. Our conjugation experiment showed the successful transfer of the bla(CMY-2)-carrying plasmid from TVGHEC01 into TVGHKP60. The transconjugant showed both high virulence and the multidrug-resistant phenotype, as did TVGHKP93. | en_US |
dc.language | en-us | - |
dc.relation | Antimicrob. Agents Chemother., 59(8), 5000-5002 | en_US |
dc.relation.ispartof | Antimicrobial Agents and Chemotherapy | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | amikacin; ampicillin; beta lactamase; cefazolin; cefepime; cefoxitin; ceftazidime; ceftriaxone; cefuroxime; ciprofloxacin; cotrimoxazole; ertapenem; gentamicin; imipenem; levofloxacin; beta-lactamase CMY-2; aged; animal experiment; animal model; antibiotic sensitivity; Article; bacterial gene; bacterial growth; bacterial strain; bacterial virulence; bacterium culture; bacterium identification; bacterium isolation; case report; colony forming unit; controlled study; diabetes mellitus; diabetic patient; DNA fingerprinting; Escherichia coli; feces analysis; gene transfer; growth rate; high throughput sequencing; hospital discharge; human; Klebsiella pneumoniae; lethal dose; lethality; liver abscess; male; minimum inhibitory concentration; mouse; multidrug resistance; multilocus sequence typing; murine model; nonhuman; phenotype; plasmid; priority journal; pulsed field gel electrophoresis; recurrent infection; rmpA gene; rmpA2 gene; septicemia; survival rate; treatment duration; treatment response; very elderly; wild type; enzymology; Escherichia coli; Escherichia coli infection; feces; genetics; Klebsiella infection; Klebsiella pneumoniae; liver abscess; microbiology; virulence; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Feces; Humans; Klebsiella Infections; Klebsiella pneumoniae; Liver Abscess; Plasmids; Virulence | - |
dc.title | Transfer of CMY-2 Cephalosporinase from Escherichia coli to Virulent Klebsiella pneumoniae Causing a Recurrent Liver Abscess | en_US |
dc.identifier.doi | 10.1128/AAC.00492-15 | - |
dc.relation.pages | 5000-5002 | en_US |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Microbiology | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-1595-6801 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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