Molecular Mechanism of Invasion and Metastasis in Human Hepatocellular Carcinoma
Date Issued
2000-07-31
Date
2000-07-31
Author(s)
李伯皇
DOI
892314B002216
Abstract
The expression levels of β-catenin ,
connexin 43, connexin 32 and E-cadherin
were performed by Western blotting. In
primary and recurrent HCC cases, the
expression level of β-catenin and connexin
43 in tumorous liver were higher than in
non-tumorous liver. But the expression of
connexin 32 and E-cadherin were decrease.
In tumorous liver, there were significant
difference of β-catenin, connexin 43 from
recurrent HCC cases and those from
primary HCC cases was compared, and the
ratio was 1.6 and 2.2. Whereas no
significant difference for connexin 32 and
E-cadherin express level were observed
between primary HCC and recurrent HCC
cases. The results indicatedβ-catenin,
connexin 43 may play important role in
tumorous liver from patients with recurrent
HCC.
Subjects
recurrent HCC
connexin 43
Publisher
臺北市：國立臺灣大學醫學院外科
Type
report
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