Pro- and Anti-Angiogenesis Effects of Resveratrol
Resource
IN VIVO v.21 n.2 pp.365-370
Journal
IN
Journal Volume
VIVO
Journal Issue
n.2
Pages
365-370
Date Issued
2007
Date
2007
Author(s)
CHEN, YUN
TSENG, SHENG-HONG
Abstract
Resveratrol, a natural polyphenol, has a variety of effects including protection against ischemia-reperfusion injury, and antitumor and chemopreventive action against malignant tumors. In recent years, resveratrol has been found to exert pro- and anti-angiogenic effects, depending on the situation. For example, pro-angiogenic effects are noted in the peri-infarct myocardium, whereas resveratrol inhibits angiogenesis in tumors. In this article, a review of the literature concerning both pro -angiogenic and anti- angiogenic effects of resveratrol and the underlying mechanisms of its effects on angiogenesis is presented.
Subjects
resveratrol
angiogenesis
pro-angiogenesis
anti-angiogenesis
review
Type
journal article