https://scholars.lib.ntu.edu.tw/handle/123456789/192399
標題: | The Prognostic Significance of Tumor Angiogenesis in Taiwanese Patients with Invasive Ductal Breast Carcinomas | 作者: | HUANG, CHIUN-SHENG CHANG, KING-JEN |
公開日期: | 1998 | 卷: | v.134 | 期: | n.1 | 起(迄)頁: | 7-14 | 來源出版物: | CANCER LETTERS | 摘要: | Angiogenesis plays an important role in tumor growth and metastasis. We performed an immunohistochemical study by anti-CD31 antibody to investigate the prognostic significance of microvessel count (MVC) in 163 Taiwanese patients with primary invasive ductal breast carcinomas. Univariate analysis revealed that MVC per 200× field correlated significantly with disease-free (P < 0.001) and overall survival (P < 0. 0008). In 74 patients with node- negative tumors, MVC also significantly correlated with disease-free (P < 0.03) and overall survival (P < 0.007). Multivariate Cox regression analysis demonstrated that MVC is an independent factor in predicting disease-free (P < 0. 02) and overall survival (P < 0.02). Our study confirms that tumor angiogenesis as measured by MVC is a reliable independent prognostic factor of breast cancer. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/92799 |
顯示於: | 醫學系 |
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