https://scholars.lib.ntu.edu.tw/handle/123456789/193161
標題: | The Influence of Helicobacter Pylori Infection on the Development of Gastric Ulcer in Symptomatic Patients after Bariatric Surgery | 作者: | YANG, CHANG-HSUEH LEE, WEI-JEI WANG, HSIH-HSI HUANG, SHIH-PEI LIN, JAW-TOWN WU, MING-SHIANG |
關鍵字: | gastric ulcer;bariatric surgery;morbid obesity;Helicobacter pylori;gastroplasty;gastric bypass | 公開日期: | 2006 | 卷: | v.16 | 期: | n.6 | 起(迄)頁: | 735-739 | 來源出版物: | OBESITY SURGERY | 摘要: | Background: There are few data relating to the role of H. pylori infection and surgical procedures on the occurrence of gastric ulcer following bariatric surgery. Methods: Subjects with upper gastrointestinal symptoms after bariatric surgery and receiving gastroscopic examinations were prospectively enrolled. All clinical data including age , sex, BMI before surgery, and surgical method were recorded . IgG antibodies against H. pylori were measured in preoperative serum by enzyme-linked immunosorbent assay ( ELISA). Results: A cohort of 636 patients undergoing laparoscopic vertical banded gastroplasty (LVBG) or Roux-en- Y gastric bypass (LRYGBP) was recruited. The seropositivity of H. pylori in symptomatic and asymptomatic patients after surgery was 39%.(32/82) and 39 .7% (220/554) respectively. Endoscopic examinations revealed that 22 (26.8 %) of 82 symptomatic patients had a gastric ulcer. Comparison of demographic characteristics between patients with ulcer (n = 22) and patients without ulcer (n = 60) showed no difference in distribution of gender, age, BMI, and seroprevalence of H. pylori (27.3%, 6/22 vs 43.3%, 26/60, P= 0.212). Patients undergoing LRYGBP showed a higher rate of gastric ulcer (45.5%, 10/22) when compared to patients undergoing LVBG (20 %, 12/60; P = 0.027). Conclusion: Gastric ulcers in symptomatic patients following laparoscopic bariatric surgery are related to surgical procedures rather than exposure to A pylori infection. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/92902 |
顯示於: | 醫學系 |
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