Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. School of Medicine / 醫學系
  4. Clinical Characteristics and Outcome of Morbidly Obese Bariatric Patients with Concurrent Hepatitis B Viral Infection
 
  • Details

Clinical Characteristics and Outcome of Morbidly Obese Bariatric Patients with Concurrent Hepatitis B Viral Infection

Resource
OBESITY SURGERY v.18 n.5 pp.589-594
Journal
Obesity Surgery
Pages
589-594
Date Issued
2008
Date
2008
Author(s)
LEE, WEI-JEI
WANG, WEU
LEE, YI-CHIH
HUANG, MING-TE
DOI
10.1007/s11695-007-9346-1
URI
http://ntur.lib.ntu.edu.tw//handle/246246/174633
Abstract
Background Bariatric surgery is the only effective and long- lasting treatment of morbidly obese patients. However, the safety and efficacy of bariatric surgery in patients with hepatitis B viral (HBV) infection is not clear. The aim of the present study is to investigate weather HBV infection influences clinic features and outcomes of bariatric surgery . Methods The preoperative seropositivity of HBV surface antigen (HBsAg) using radioimmunoassay was determined in 592 patients (481 female, 111 male: mean age 30.5 +/- 8.1 years ; mean body mass index [BMI] 43.1 +/- 6. 0) who had undergone bariatric surgery (209 banding and 383 gastric bypass ) for their morbid obesity in the past 5 years. All the clinical data were prospectively collected and stored. Results The overall seroprevalence of HbsAg was 18.8%. Morbidly obese patients positive for HBV infection were associated with older age and higher diastolic blood pressure, but not with sex, BMI, liver enzyme, blood lipid, and glucose levels. Although minigastric bypass (MGB) had a better weight reduction than gastric banding, there was no difference in weight reduction between patients who were positive and negative for HBV infection. The weight loss curves and resolution of obesity-related comorbidities were similar between the two groups except the postoperative aspartate transaminase (AST) and alanine transaminase (ALT) were significantly higher in patients who were positive for HBV infection. During follow-up, two patients developed fulminating hepatitis after MGB with one mortality. Conclusion Morbidly obese patients with the existence of HBV infection do not influence the outcome of bariatric surgery , but continuing monitor of the liver function is indicated.
Subjects
morbid obesity
bariatric surgery
HBV infection
minigastric bypass
SDGs

[SDGs]SDG3

Other Subjects
alanine aminotransferase; aspartate aminotransferase; glucose; hepatitis B surface antigen; liver enzyme; adult; age distribution; article; bariatric surgery; body mass; clinical feature; comorbidity; concurrent infection; controlled study; diastolic blood pressure; female; follow up; gastric banding; glucose blood level; hepatitis; hepatitis B; human; lipid blood level; major clinical study; male; morbid obesity; postoperative period; preoperative evaluation; priority journal; radioimmunoassay; seroprevalence; sex; stomach bypass; surgical mortality; treatment outcome; weight reduction; Adult; Alanine Transaminase; Aspartate Aminotransferases; Comorbidity; Fatty Liver; Female; Gastric Bypass; Gastroplasty; Hepatitis B; Humans; Liver; Male; Obesity, Morbid; Radioimmunoassay
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science