The Development of Hepatocellular Carcinoma among Prospectively Followed Children with Chronic Hepatitis B Virus Infection
Resource
JOURNAL OF PEDIATRICS v.144 n.3 pp.397~399
Journal
JOURNAL OF PEDIATRICS
Journal Volume
v.144
Journal Issue
n.3
Pages
397-399
Date Issued
2004
Date
2004
Author(s)
WEN, WAN-HSIN
CHANG, MEI-HWEI
HSU, HONG-YUAN
NI, YEN-HSUAN
CHEN, HUEY-LING
Abstract
We prospectively followed 426 children with chronic hepatitis B virus infection. During 6250 person-years, 2 boys developed hepatocellular carcinoma. with an incidence of 32 per 100,000 person-years. Both had e antigen seroconversion in early childhood and cirrhosis. Early e antigen seroconversion and/or cirrhosis may be risk factors for hepatocellular carcinoma.
SDGs
Type
journal article