https://scholars.lib.ntu.edu.tw/handle/123456789/194499
標題: | Childhood Severe Acute Respiratory Syndrome in Taiwan and How to Differentiate It from Childhood Influenza Infection | 作者: | CHANG, LUAN-YIN HUANG, FU-YUAN WU, YI- CHUN SU, IH-JEN CHIU, NAN-CHANG CHEN, KOW-TONG LIN, TING-HSIANG PENG, SHINN-FORNG KAO, CHUAN-LIANG LEE, CHIN-YUN HUANG, LI-MIN |
公開日期: | 2004 | 卷: | v.158 | 期: | n.11 | 起(迄)頁: | 1037-1042 | 來源出版物: | ARCHIVES OF PEDIATRICS AND ADOLESCENT MEDICINE | 摘要: | OBJECTIVE: To investigate clinical features and outcomes of children in Taiwan with laboratory-confirmed severe acute respiratory syndrome (SARS) vs those of children with influenza to differentiate the 2 diseases. DESIGN, SETTING, AND PARTICIPANTS: Patients 20 years or younger with clinical , epidemiological, and laboratory evidence of SARS from March to July 2003 vs children with virus culture-confirmed influenza in a 1:1 age- and sex-matched control group. MAIN OUTCOME MEASURES: Rates of symptoms, abnormal laboratory data, and outcomes of recovery, sequelae, or death. RESULTS: The 15 SARS patients (9 girls and 6 boys) had a median age of 17 years (age range, 4-20 years). Nine patients (60%) were infected through household contact, 4 (27%) nosocomially, 1 (7%) through contact with a neighbor, and 1( 7%) after returning from Hong Kong. All 15 patients had fever, 3 (20%) had chills, and 11 (73%) had cough. Only 1 patient (7%) had sputum production; 1 (7%) had rhinorrhea. At presentation, 5 patients (33 %) had leukopenia, 6 (40%) had lymphopenia, and 5 (33%) had monocytopenia. All children recovered without sequelae. Children with SARS had significantly lower incidences of rhinorrhea (odds ratio [OR ], 0.01; 95% confidence interval [CI], 0.00-0.09), sputum production (OR, 0.10; 95% CI, 0.02-0.63), and sore throat ( OR, 0.17; 95% CI, 0.03-0.85) than children with influenza. Both groups had similar incidences of leukopenia or lymphopenia, but SARS patients had a significantly higher incidence of monocytopenia (33% vs 0%, P = .04). CONCLUSIONS : Childhood SARS is usually not fatal. The absence of rhinorrhea and presence of monocytopenia in SARS may distinguish it from influenza |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/88692 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。