|Title:||Nephromegaly in the Children with Kawasaki Disease: A New Supporting Evidence for Diagnosis||Authors:||TSAU YONG-KWEI
|Issue Date:||2007||Journal Volume:||v.22||Journal Issue:||n.9||Start page/Pages:||1529-1529||Source:||PEDIATRIC NEPHROLOGY||Abstract:||
Objective: To measure the kidney size in children with Kawasaki disease ( KD) during acute stage and to delineate the condition of nephromegaly. Methods: Twenty children with KD (13 boys and 7 girls, aged from 3 to 78 months) were enrolled in our study. Kidney sizes (including kidney length and kidney volume) were measured during acute stage in these patients. Twenty age- and sex-matched healthy children and 15 febrile children served as healthy controls and fever controls. Left kidney length and age were used for correlation analysis and analysis of covariance. Results: Kidney lengths in patients with KD were significantly larger than those of healthy children (p<0.001). The mean SD score of kidney length was 2.54± 0.97 for these patients (p<0.001 , vs -0.23±0.82 in normal control). Kidney volume analysis yields the similar result (51.83±17. 93cm3 vs 35. 62±11.24 cm3, p=0.001). There was no kidney enlargement in the fever controls. Up to 70% of the children with KD have absolute nephromegaly (> mean+2 SD). This incidence is as frequent as that of lymphadenopathy and extremities change, the 2 diagnostic criteria of KD. Conclusion: These results confirm the presence of large kidneys in the children with KD and also provide another useful indicator for KD diagnosis if the diagnostic criteria is not yet well established.
|Appears in Collections:||醫學系|
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