|Title:||Seroprevalence of Rubella Infection after National Immunization Program in Taiwan: Vaccination Status and Immigration Impact||Authors:||WANG, I-JEN
CHEN, TONY HSIU-HSI
|Keywords:||seroprevalence;foreign brides;chronic rubella syndrome||Issue Date:||2007||Journal Volume:||VIROLOGY||Journal Issue:||n.1||Start page/Pages:||97-103||Source:||JOURNAL OF MEDICAL||Abstract:||
Rubella vaccination was implemented nationwide in 1992 in Taiwan. A cross -sectional survey was conducted to determine the age-specific seroprevalence of anti-rubella in female students aged 722 years old and women of reproductive age in Taipei County. Seropositivity of anti-rubella antibodies was defined as a serum IgG level >= 10 IU/ml tested by enzyme immunoassay. Information on possible predictors of anti-rubella seronegativity was obtained from structured questionnaire interview. Multivariate-adjusted odds ratios ( ORm) with their 95% confidence interval (Cl) were derived for each predictor using multiple logistic regression analysis. A total of 826 female students and 318 women were recruited. Anti-rubella seropositive rates were 98.3% (282/ 287), 99.6% ( 234/235), 96.8% (179/185), 92.4% (110/119), 81. 4% (197/242), and 89.5% ( 68/76) for the age groups of 7-9, 11-13,15-17, 19-22, 25-33, and 34-44 years old, respectively . Among female students, negative serologyfor rubella antibodies was associated significantly with the age group and foreign nationality of mother, showing ORm (95% CI) of 1 .2 (1.06-1.27) for each year increase in age, and 20.9 (6.31 -68.97), respectively. Among women at the reproductive age, low maternal education level 91.6 (9.12- 920.74), unmarried status 21.2 (6.1672.89), and no rubella vaccination 98. 9 (11 .64840.25) were associated significantly with an increased evidence of seronegativity to rubella. The National Rubella Vaccination Program has led to herd immunity of school girls . However, in order to eradicate the Rubella syndrome, greater effort is required to vaccinate foreign brides in Taiwan.
|Appears in Collections:||醫學系|
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