Sexual Precocity Due to Intracranial Human Chorionic Gonadotropin- Secreting Tumor: Report of a Case
Resource
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION v.93 n.4 pp.346-348
Journal
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
Journal Volume
v.93
Journal Issue
n.4
Pages
346-348
Date Issued
1994
Date
1994
Author(s)
HSIAO, PEI-HUNG
TSAI, WEN-YU
HUANG, SHIN-HUNG
LI, YIU-WAH
LIN, SWEI-MING
Abstract
Human chorionic gonadotropin (HCG)-secreting tumors are one of the causes of isosexual precocity in boys. A sseven- year-old boy had been noted to have an increased appetite, accelerated growth and the development of pubic hiar in the previous three months. He had an elevated serum testosterone level (16.79ng/mL). However, the response of luteinizing- hormone and follicle-stimulating-hormone to gonadotropin relrasing hormone stimulation was suppressed. An intracranial tumor at the left thalamus was disclosed by a magnetic resonance image scan of the head, and elevated HCG level (120 mlU/mL) was also noted. Sexual precocity due to an intracranial HCG secreting tumor was diagnosed and a partial resection of the tumor followed by radiotherapy was carried out. His serum testosterone and HCG levels became undetectable, and the secondary sexual characteristics regressed after ureatment.#1301
Type
journal article