https://scholars.lib.ntu.edu.tw/handle/123456789/194846
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 小兒科 | en |
dc.contributor.author | CHAN, PEI-CHUN | en |
dc.contributor.author | CHEN, HUEY-LING | en |
dc.contributor.author | KONG, MAN-SHAN | en |
dc.contributor.author | HUANG, FU-CHEN | en |
dc.contributor.author | LEE, HONG-CHANG | en |
dc.contributor.author | LIN, CHIEH-CHUNG | en |
dc.contributor.author | LIU, CHING-CHUAN | en |
dc.contributor.author | LEE, I- HSIEN | en |
dc.contributor.author | WU, TZEE-CHUNG | en |
dc.contributor.author | WU, SHU-FEN | en |
dc.contributor.author | NI, YEN-HSUAN | en |
dc.contributor.author | HSU, HONG-YUAN | en |
dc.contributor.author | CHANG, MEI-HWEI | en |
dc.creator | 詹珮君;陳慧玲;江文山;黃福辰;李宏昌;林捷忠;劉清泉;李ㄧ賢;吳子聰;吳淑芬;倪衍玄;許宏遠;張美惠 | zh_TW |
dc.creator | CHAN, PEI-CHUN;CHEN, HUEY-LING;KONG, MAN-SHAN;HUANG, FU-CHEN;LEE, HONG-CHANG;LIN, CHIEH-CHUNG;LIU, CHING-CHUAN;LEE, I- HSIEN;WU, TZEE-CHUNG;WU, SHU-FEN;NI, YEN-HSUAN;HSU, HONG-YUAN;CHANG, MEI-HWEI | en |
dc.date | 2005 | en |
dc.date.accessioned | 2008-12-22T03:17:52Z | - |
dc.date.accessioned | 2018-07-11T17:54:15Z | - |
dc.date.available | 2008-12-22T03:17:52Z | - |
dc.date.available | 2018-07-11T17:54:15Z | - |
dc.date.issued | 2005 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/92602 | - |
dc.description.abstract | Aim: To investigate the factors affecting the outcome of fulminant hepatic failure (FHF) in children in relation to hepatitis B virus (HBV) infection. Methods: Retrospective review of a total of 94 cases (61 males and 33 females, aged from 1 month to 15 years) recruited from nine tertiary referral centers in Taiwan from 1985 to 1999. Results: The overall mortality rate was 75%. Patients in the mortality group were of an older age, had higher peak total bilirubin levels, a longer prothrombin time, and a lower percentage of HBV positivity (P < 0.001, P = 0.003, P = 0.0027 and P = 0. 042, respectively). Mortality was 65% in the HBV positive (n = 42) and 83% in the HBV negative (n = 52) group (P = 0.05) . In the HBV positive group, the prothrombin time was noted to be the single factor affecting outcome (P = 0.036). In the HBV negative group, older age and higher peak value of total serum bilirubin were suggestive of poor survival rate (P < 0.001 and P = 0.006, respectively). Multivariate analysis revealed that total bilirubin was the single factor affecting outcome in the HBV-negative group. The mortality rate of HBV positive children in three consecutive time periods without liver transplantation ( 1985–1989, 1990–1994, 1995–1999) decreased gradually (91, 67 and 38%, respectively, with P = 0.027). This change was not observed in HBV- negative cases. Conclusions: Hepatitis B virus positive FHF had a lower mortality rate than HBV negative FHF, with each group having different factors affecting mortality. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY v.20 n.8 pp.1223-1227 | en |
dc.relation.ispartof | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
dc.subject | children | en |
dc.subject | fulminant hepatic failure | en |
dc.subject | prognosis | en |
dc.subject | mortality | en |
dc.subject | viral hepatitis | en |
dc.subject.classification | [SDGs]SDG3 | - |
dc.title | Factors Affecting the Mortality of Pediatric Fulminant Hepatic Failure in Relation to Hbv Infection | en |
dc.type | journal article | en |
dc.relation.pages | 1223-1227 | - |
dc.relation.journalvolume | v.20 | - |
dc.relation.journalissue | n.8 | - |
item.languageiso639-1 | en_US | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
顯示於: | 醫學系 |
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