https://scholars.lib.ntu.edu.tw/handle/123456789/194878
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 小兒科 | en |
dc.contributor.author | CHENG, CHI-HUI | en |
dc.contributor.author | TSAU, YONG-KWEI | en |
dc.contributor.author | LIN, TZOU-YIEN | en |
dc.creator | 鄭積慧;曹永魁;林奏延 | zh-tw |
dc.creator | CHENG, CHI-HUI;TSAU, YONG-KWEI;LIN, TZOU-YIEN | en |
dc.date | 2006 | en |
dc.date.accessioned | 2008-12-22T03:22:52Z | - |
dc.date.accessioned | 2018-07-11T17:54:21Z | - |
dc.date.available | 2008-12-22T03:22:52Z | - |
dc.date.available | 2018-07-11T17:54:21Z | - |
dc.date.issued | 2006 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/92635 | - |
dc.description.abstract | OBJECTIVE. Effective treatment of acute lobar nephronia (ALN ) can prevent its progression to renal abscess. The goal of this prospective study was to compare the treatment efficacy for pediatric patients who had ALN with a 3- vs 2-week intravenous plus oral antimicrobial-therapy regimen.METHODS. Patients who were suspected of having an upper urinary tract infection underwent a systematic scheme of ultrasonographic and computed tomographic(CT) evaluation for ALN diagnosis. Patients with positive CT findings were enrolled and randomly allocated with serial entry for either a total 2-week or a 3-week antibiotic treatment regimen. Antibiotics were changed from an intravenous form to an oral form 2 to 3 days after defervescence of fever. Follow-up clinical evaluations and urine-culture analyses were performed 3 to 7 days after cessation of antibiotic treatment. Patients with persistent infection or relapse were considered as treatment failures. RESULTS.A total of 80 patients with ALN were enrolled. Forty-one patients were treated with a 2-week antimicrobial protocol, and the other 39 patients were treated with a 3-week course. Seven treatment failures, 1 persistent infection, and 6 infection relapses were identified, all of which were in the 2-week treatment group. Prolonged fever before admission and positive Escherichia coli growth (105 colony-forming units per mL) in urine culture were noted as risk factors for treatment failure. All treatment failures were managed successfully with an additional 10-day antibiotic course. CONCLUSION.A total of 3 weeks of intravenous and oral antibiotic therapy tailored to the pathogen noted in cultures should be the treatment of choice for pediatric patients with ALN. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | PEDIATRICS v.117 n.1 pp.E84-E89 | en |
dc.relation.ispartof | PEDIATRICS | - |
dc.subject | acute focal bacterial nephritis | en |
dc.subject | antibiotic treatment, treatment failure | en |
dc.subject | efficacy evaluation, CT scan | en |
dc.title | Effective Duration of Antimicrobial Therapy for the Treatment of Acute Lobar Nephronia | en |
dc.type | journal article | en |
dc.relation.pages | E84-E89 | - |
dc.relation.journalvolume | v.117 | - |
dc.relation.journalissue | n.1 | - |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en_US | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
顯示於: | 醫學系 |
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