https://scholars.lib.ntu.edu.tw/handle/123456789/194928
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 小兒科 | en |
dc.contributor.author | CHIANG, BOR-LUEN | en |
dc.creator | 江伯倫 | zh-tw |
dc.creator | CHIANG, BOR-LUEN | en |
dc.date | 2001 | en |
dc.date.accessioned | 2008-12-29T06:10:21Z | - |
dc.date.accessioned | 2018-07-11T17:54:30Z | - |
dc.date.available | 2008-12-29T06:10:21Z | - |
dc.date.available | 2018-07-11T17:54:30Z | - |
dc.date.issued | 2001 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/94820 | - |
dc.description.abstract | Objective: To determine the effects of the probiotic lactic acid bacterium, Lactobacillus rhamnosus HN001, on natural cellular immunity when delivered orally in normal low-fat milk (LFM) or lactose-hydrolized low-fat milk (LFM-LH). Design: A three stage, pre-post intervention trial, spanning nine weeks.Setting: Taipei Medical College Hospital, Taipei , Taiwan.Subjects: Fifty-two healthy middle-aged and elderly volunteers (17 males, 35 females; median age 63.5, range 44 -80).Interventions: Stage 1 ( run-in diet): 25g/200 mL reconstituted LFM powder, twice daily for 3 weeks . Stage 2 ( probiotic intervention): LFM or LFM-LH, supplemented with 10(9 ) CFUs/g L. rhamnosus HN001 in each case, for 3 weeks. Stage 3 (wash-out): LFM for 3 weeks.Measures of Outcome: In vitro phagocytic capacity of peripheral blood polymorphonuclear (PMN) leukocytes; in vitro tumoricidal activity of natural killer (NK) leukocytes.Results: Immunological responses were unaffected by the run-in diet of LFM alone. In contrast, the relative proportion of PMN cells showing phagocytic activity increased by 19% and 15%, respectively, following consumption of HN001 in either LFM or LFM-LH; the relative level of NK cell tumor killing activity increased by 71% and 147%. In most cases these levels declined following cessation, but remained above baseline.Conclusion: Dietary consumption of L. rhamnosus HN 001, in a base of low-fat milk or lactose-hydrolyzed low- fat milk, appears to enhance systemic cellular immune responses and may be useful as a dietary supplement to boost natural immunity. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION v.20 n.2 pp.149-156 | en |
dc.relation.ispartof | JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION | - |
dc.subject | Lactobacillus | en |
dc.subject | rhamnosus immune enhancement | en |
dc.subject | phagocytosis | en |
dc.subject | NK cells | en |
dc.subject | ELDERLY SUBJECTS | en |
dc.subject | NHANCEMENT | en |
dc.title | Systemic Immunity-Enhancing Effects in Healthy Subjects Following Dietary Consumption of the Lactic Acid Bacterium Lactobacillus Rhamnosus Hn001 | en |
dc.type | journal article | en |
dc.relation.pages | 149-156 | - |
dc.relation.journalvolume | v.20 | - |
dc.relation.journalissue | n.2 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en_US | - |
item.cerifentitytype | Publications | - |
顯示於: | 醫學系 |
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