https://scholars.lib.ntu.edu.tw/handle/123456789/194942
Title: | A Comparison of Safety, Tolerability and Immunogenicity of Oka/Merck Varicella Vaccine and Varilrix(Tm) in Healthy Children | Authors: | HUANG, LI-MIN | Keywords: | varicella zoster virus;immunogenicity;varicella vaccination;ANTIBODY;PROTECTION | Issue Date: | 2002 | Journal Volume: | v.20 | Journal Issue: | n.23-24 | Start page/Pages: | 2942-2949 | Source: | VACCINE | Abstract: | This study compared safety, tolerability, and immunogenicity of the Oka/ Merck varicella vaccine and VARILRIX(TM) [Oka- RIT strain SmithKline Beecham Biologicals] in healthy children 12-24 months of age. Subjects were randomized in this double blind study to receive either a single dose of Oka/Merck varicella vaccine, (similar to50,000 plaque forming units ( PFU), Group A or similar to16,000 PFU, Group B) or 1 dose of VARILRIX(TM), (similar to40,000 PFU/dose, Group C). Safety profiles in each treatment group were similar. The proportions of subjects achieving a 6-week postvaccination titer greater than or equal to5 gpELISA units in Groups A, B or C were 97.1, 95.2 and 85.6%, respectively. (C) 2002 Elsevier Science Ltd. All rights reserved. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/94834 |
Appears in Collections: | 醫學系 |
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