Myasthenia Gravis:Population Differences in Disease Expression and Acetylcholine Receptor Antibody Titers Between Chinese and Caucasians
Resource
Neurology, v.87 p.1854-1857
Journal
Neurology
Pages
1854
Date Issued
1987
Date
1987
Author(s)
Hsieh, Kue-Hsiung
Abstract
Clinical features and anti-acetylcholine receptor (AChR) titers were compared in Chinese (n = 258) and Caucasian (n = 258) myasthenia gravis populations. The former had more early onset and ocular cases, lacked the Caucasian late onset peak, and had fewer severe cases. The distribution of anti-AChR titers was broadly similar in the two populations, and their sera reacted equally well with AChR in both races. The significantly lower (chi 2 = 14.6; p less than 0.001) median anti-AChR titer in the Chinese population can be accounted for by the higher frequency of ocular cases and lower frequency of moderate or severely affected cases.
SDGs
Type
journal article