The Assessment of Normal Fetal Liver Volume by Three-Dimensional Ultrasound
Resource
ULTRASOUND IN MEDICINE AND BIOLOGY v.29 n.8 pp.1123-1129
Journal
ULTRASOUND IN MEDICINE AND BIOLOGY
Journal Volume
v.29
Journal Issue
n.8
Pages
1123-1129
Date Issued
2003
Date
2003
Author(s)
Chang, Chiung-Hsin
Yu, Chen-Hsiang
Chang, Fong-Ming
Ko, Huei-Chen
Chen, Hsi-Yao
Abstract
Liver volume (LIVV) is very important in determining the status of fetal growth. However, to measure human fetal LIVV in utero precisely and noninvasively is not an easy task. With the recent advancement of three- dimensional (3-D) ultrasound (US), the limitation in assessing fetal LIVV by 2 -D US can be overcome. The purpose of this study was to establish a normal reference chart of fetal LIVV for clinical use. A prospective and cross-sectional study using 3-D US was undertaken to assess the fetal LIVV in normal pregnancy. In total, 226 singleton fetuses ranging between 20 and 40 weeks of gestation and fitting the criteria of normal pregnancies were enrolled in this study. Our results showed that fetal LIVV is highly correlated with the gestational age (GA). Furthermore, using GA as the independent variable and fetal LIVV as the dependent variable, the best- fit regression equation was LIVV (mL) = - 398.26 + 46.199 xGA - 1.7567 x GA(2) + 0.0236 x GA(3)(r = 0 . 97, n = 226, p < 0.0001), with SD of LIVV ( mL) = 1.2533 x( 0.77956 + 0.17267 x GA). These common indexes of fetal biometry, such as biparietal diameter (BPD), occipitofrontal diameter (OFD ), head circumference (HCi), abdominal circumference (ACi), femur length ( FL), and estimated fetal weight (EFW), were all highly correlated with fetal LIVV ( all p < 0.0001). In conclusion, our data of fetal LIVV assessed by 3-D US can serve as a useful reference in evaluating fetal growth status during normal gestation. (C) 2003 World Federation for Ultrasound in Medicine Biology.
Subjects
three-dimensional ultrasound
fetus
liver volume
SDGs