https://scholars.lib.ntu.edu.tw/handle/123456789/198048
標題: | The Diagnostic Value of Sensory Evoked Potentials in Pediatric Wilson Disease | 作者: | HSU, Y-S CHANG, YANG-CHYUAN LEE, WANG-TSO NI, YEN-HSUAN HSU, HONG-YUAN CHANG, MEI-HWEI |
關鍵字: | DEGENERATION | 公開日期: | 2003 | 卷: | v.29 | 期: | n.1 | 起(迄)頁: | 42-45 | 來源出版物: | PEDIATRIC NEUROLOGY | 摘要: | We studied the sensory evoked potentials in pediatric Wilson disease to verify their subclinical neurologic involvement and to elucidate the role of cirrhosis in abnormal evoked potentials in non-neurologic Wilson disease. Thirty children (17 male, 13 female), diagnosed with Wilson disease before 18 years, were enrolled. The mean age during studies was 15 . 8 +/- 6.3 years, and disease duration since diagnosis was 3 . 0 +/- 3.3 years. In 12 neurologic Wilson disease cases, there were prolonged interpeak latencies of brainstem auditory evoked potentials III-V, IN, somatosensory evoked potentials N13-N20 (P < 0.01 vs controls and non- neurologic cases), and P100 latency (P < 0.01 vs controls). All 12 patients had at least one abnormal evoked potential, including 91.7% brainstem auditory, 58.3% somatosensory, and 25% visual evoked potentials. In 18 non-neurologic Wilson disease cases, there were still prolonged interpeak latencies for brainstem auditory evoked potentials IN and somatosensory evoked potentials N13-N20 (P < 0.05 vs controls), with 27.8% of them having at least one abnormal evoked potential, including 16.6% brainstem auditory, 5.6% somatosensory, and 11.1% visual evoked potentials . In those with non-neurologic Wilson disease, there were no significant differences in all the evoked potential parameters between the cirrhotic and non-cirrhotic patients. (C) 2003 by Elsevier Inc. All rights reserved. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/99668 |
顯示於: | 醫學系 |
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