|Title:||A predictive model for postoperative intraocular pressure among patients undergoing laser in situ keratomileusis (LASIK)||Authors:||Yang, Chia-Ching
|Issue Date:||Oct-2005||Publisher:||Taipei:National Taiwan University Dept Comp Sci Informat Engn||Start page/Pages:||685-691||Source:||BIOINFORMATICS 22||Abstract:||
PURPOSE: The aim of this study was to develop a
predictive model based on preoperative variables for estimating
postoperative intraocular pressure (IOP) of those
eyes undergoing LASIK surgery, to predict the amount of
underestimated IOP after LASIK for myopia and myopic
DESIGN: Pretest-post-test longitudinal study.
METHODS: Both eyes of 193 eligible subjects who
underwent LASIK procedures at the Department of
Ophthalmology, National Taiwan University Hospital,
from July 2000 to December 2002 for myopia and
myopic astigmatism were identified to build up the
predictive models. IOPs were measured with noncontact
air-puff tonometry. Information on age, gender, preoperative
central corneal thickness (CCT), preoperative central
corneal curvature (CCK), preoperative spherical
equivalent refractive error, and ablation depth was collected
and applied for predicting postoperative IOP after
LASIK based on linear mixed model.
RESULTS: Significant predictors for postoperative IOP
after myopic LASIK procedures included age, gender,
preoperative IOP, ablation depth, preoperative CCT, and
preoperative spherical equivalent refractive errors. The
linear mixed model, taking into account these significant
preoperative correlates and the correlation of IOPs between
both eyes of the same patient, explained 91% of
the variation of postoperative IOP.
CONCLUSIONS: A statistical model was developed for
predicting the amount of underestimated IOP after
LASIK for myopia and myopic astigmatism, which is
of clinical importance to uncover ocular hypertension
among patients whose information on postoperative IOP
immediately after LASIK is not available.
|Appears in Collections:||醫學系|
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