|Title:||Fundus Abnormalities in a Patient with Type I Gaucher's Disease with 12- Year Follow-Up||Authors:||WANG, TSUNG-JEN
|Issue Date:||2005||Journal Volume:||v.139||Journal Issue:||n.2||Start page/Pages:||359-362||Source:||AMERICAN JOURNAL OF OPHTHALMOLOGY||Abstract:||
Purpose To report a case of type I Gaucher's disease with rare presentation of fundus abnormalities in long-term observation. DesignObservational case report.Methods This 53- year-old Taiwanese woman suffered from type I Gaucher's disease for 12 years, with initial presentation of hepatoslpenomegaly in 1992.Results At that time, poor vision with unusual macular change and peripheral retinal vessel leakage was also noted. She received a complete ophthalmic examination at the initial visit and again 12 years later in 2003. She was treated with imiglucerase injection during the last 4 years. However, her visual acuity was 10/200 in both eyes. The macular and peripheral retinal degenerative change progressed after 12 years. Conclusions Fundus changes associated with Gaucher's disease are uncommon. We should not neglect the possibility of retinal involvement and progression in these patients.
|Appears in Collections:||醫學系|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.