The clinical significant of perfusion and diffusion images in subacute cerebral infarct
Date Issued
2001-07-31
Date
2001-07-31
Author(s)
廖漢文
DOI
892314B002272M08
Abstract
Background: More than 20,000 new cases of
cerebrovascular diseases occurred annually in Taiwan
area. It becomes the second most common cause of
death in this country. Among them, 60% to 75% were
ischemic stroke with a trend increasing every year.
Except for those cases will die in acute stage, all of the
rest become subacute or chronic stage. In recent,
diffusion and perfusion imagings are considered as
latest and the most accurate tool for the diagnosis of
hyper-acute and acute ischemic cerebral diseases.
However, their clinical role in the subacute and
chronic stage is not studied yet.
Method: With Doppler and MRA, we can study the
status of the steno-occlusive change of the major
cerebral vessels. In the same time, we can perform the
H-MRS perfusion and diffusion imaging in them. With
analysis of the data, we may categorize the patients
into different group according their different
combination of the patterns of perfusion and diffusion
imagings. From this we can evaluate and predict the
prognosis of each patient.
This plan can be divided into 3 year:
1. We can collect about 50 cases with subacute infarct,
basic analysis according to their perfusion and
diffusion imaging can be performed in the 1st year.
2. In the 2nd year, we have to collect 100 more cases
and make a data bank, and analysis the prognosis of
the first 50 cases.
3. In the 3rd year, we have to analysis the perfusion
and diffusion imagings, clinical, and outcome in the
150 patients, and calculate their statistic
relationship.
Subjects
Cerebral ischemia
Magnetic resonance
image
image
perfusion image
diffusion image
Publisher
臺北市：國立臺灣大學醫學院放射線科
Type
journal article
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