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  4. Solitary Vertebral Collapse: Distinction between Benign and Malignant Causes
 
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Solitary Vertebral Collapse: Distinction between Benign and Malignant Causes

Resource
JOURNAL OF MAGNETIC RESONANCE IMAGING v.9 pp.635-642
Journal
JOURNAL OF MAGNETIC RESONANCE IMAGING
Journal Volume
v.9
Pages
635-642
Date Issued
1999
Date
1999
Author(s)
SHIH, TIFFANY TING-FANG
HUANG, KOU-MOU
LI, YIU-WAH
URI
http://ntur.lib.ntu.edu.tw//handle/246246/87890
Abstract
Differentiation of benign from malignant causes of vertebral compression fracture can be difficult at a single location. We studied 37 patients with solitary vertebral collapse ( SVC) in the spine using magnetic resonance imaging (MRI). Sixteen of them were found to have a benign cause of SVC, while the remaining 21 were found to have malignancy. The following four MRI characteristics were investigated: ill- or well-defined margin of the intravertebral lesion (P < 0. 005); pedicle involvement (P < 0.05); MR enhancement pattern (P < 0.005); and paravertebral soft tissue lesion (PSL) (P< 0.025). It was found that cases of malignant SVC tended to have an ill-defined margin, abnormal signal involvement of the pedicle, a marked and heterogenous MR enhancement pattern, and irregular nodular- type PSL. Pedicle change with expansile lesion totally excluded a benign cause. By using these criteria, we were able to differentiate benign or malignant causes of SVC accurately.

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