DC 欄位 | 值 | 語言 |
dc.contributor.author | 林東燦 | zh-TW |
dc.creator | 林東燦 | zh_TW |
dc.date | 1998-07-31 | zh_TW |
dc.date.accessioned | 2006-07-26T04:53:17Z | en |
dc.date.accessioned | 2018-07-12T08:58:03Z | - |
dc.date.available | 2006-07-26T04:53:17Z | en |
dc.date.available | 2018-07-12T08:58:03Z | - |
dc.date.issued | 1998-07-31 | - |
dc.identifier | 872314B002075 | en |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/27313 | - |
dc.description.abstract | Monocyte adhesion and subsequent
activation are major events that facilitate the
foreign-body reaction. These studies evaluate
the effect of semicrystalline polyamide
(Nylon-66), poly (ethylene-co-vinyl alcohol)
(EVAL), and poly (vinylidene fluoride)
(PVDF) with nonporous and porous
morphologies on the ability of monocyte
adhesion and activation to produce variable
levels of IL-1b, IL-6, and TNF-a. Results
indicated IL-1b was produced in the greatest
quantity by these polymers. In addition,
monocyte adhesion and activation on a
material may alter to a great extent dependent
on the surface morphology and wettability.
As the membrane wettability increases, the
ability of the membrane to adhere monocytes
increases but to stimulate monocyte
production of cytokines decreases. Similarly,
these membranes when prepared with porous
surfaces can enhance monocyte adhesion and
suppress monocyte activity. Therefore, the
nonporous PVDF membrane is the least
biocompatible in this work. In contrast, the
hydrophilic membrane Nylon-66 with porous
surface is the least stimulating of monocyte
cytokine production when compared to all of
the other membranes evaluated with
nonporous or porous surface. These studies
provide important insight into conditions that
modulate monocyte activity in response to
the substratum morphology and wettability. | en |
dc.format | application/pdf | en |
dc.format.extent | 45749 bytes | en |
dc.format.mimetype | application/pdf | en |
dc.language | zh-TW | - |
dc.language.iso | zh_TW | zh_TW |
dc.publisher | 臺北市:國立臺灣大學醫學院檢驗醫學科 | zh_TW |
dc.rights | 國立臺灣大學醫學院檢驗醫學科 | zh_TW |
dc.subject | surface morphology | en |
dc.subject | surface wettability | en |
dc.subject | monocyte | en |
dc.subject | adhesion | en |
dc.subject | activation | en |
dc.title | 不同薄膜之表面特性與生物適應性之影響 | zh_TW |
dc.type | journal article | en |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/27313/1/872314B002075.pdf | - |
dc.coverage | 計畫年度:87;起迄日期:1997-08-01/1998-07-31 | zh_TW |
item.languageiso639-1 | zh_TW | - |
item.fulltext | with fulltext | - |
item.grantfulltext | open | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.orcid | 0000-0002-5773-3200 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系
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