Gender differences in the distribution of bone mass in the third lumbar vertebra and its age-related changes
Date Issued
2000-07-31
Date
2000-07-31
Author(s)
蔡克嵩
DOI
892314B002084
Abstract
Compression fractures occur mainly at
the vertebral body. Variations in the
distribution of bone mass in a vertebra, if
undefined, may bias the ability of the
acquired bone mineral density values, which
was usually measured posteroanteriorly, to
predict the risk of fractures. To evaluate the
effects of age and gender on the distribution
of bone mineral content in the third lumbar
vertebrae. We performed a cross sectional
study on the distribution of bone mineral
content in the third lumbar vertebrae. The
bone mineral content of the whole L3
including the L3 vertebral body and the
posterior segment was measured using a
lateral approach with a dual energy x-ray
absorptiometer on 177 healthy Taiwanese
adults including 65 men, and 55
premenopausal and 57 postmenopausal
women. The proportion of bone mineral
content (BMC) in the vertebral body was
significantly lower in premenopausal women
than in age-matched men (39.1±0.9% vs.
50.0±1.7%, P< 0.0001). Furthermore,
while postmenopausal women showed a
decreased proportion of BMC in the vertebral
body with increased age (about -0.0022 per
year, p=0.0001), premenopausal women and
men showed a sustained proportion. Thus,
the proportion of BMC distributed in the
body of L3 vertebrae was lower in women
than in men. The discrepancy of this
parameter between the genders was even
larger with increased ages.
Subjects
gender
age
L3 vertebral body
bone content distribution
Publisher
臺北市：國立臺灣大學醫學院檢驗醫學科
Type
journal article
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