Infective Endocarditis Complicated with Progressive Heart Failure Due to Beta-Lactamase-Producing Cardiobacterium Hominis
Resource
JOURNAL OF CLINICAL MICROBIOLOGY v.38 n.5 pp.2015-2017
Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Journal Volume
v.38
Journal Issue
n.5
Pages
2015-2017
Date Issued
2000
Date
2000
Author(s)
LU, PO-LIANG
HSUEH, PO-REN
HUNG, CHIEN-CHING
TENG, LEE-JENE
JANG, TSRANG-NENG
LUH, KWEN-TAY
Abstract
We describe a 66-year-old woman with infective endocarditis due to Cardiobacterium hominis whose condition, complicated by severe aortic regurgitation and congestive heart failure, necessitated aortic valve replacement despite treatment with ceftriaxone followed by ciprofloxacin. The blood isolate of C. hominis produced beta-lactamase and exhibited high -level resistance to penicillin (MIC, greater than or equal to 256 mu g/ml ) and reduced susceptibility to vancomycin (MIC, 8 mu g/ml).
Subjects
BACTEREMIA