|Title:||High Prevalence of Hyperuricemia in Elderly Taiwanese||Authors:||蔡克嵩
|Keywords:||hyperuricemia;metabolic syndrome (MS);elderly;indigenous;mountainous;serum urate||Issue Date:||2005||Journal Volume:||v.14||Journal Issue:||n.3||Start page/Pages:||285-292||Source:||ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION||Abstract:||
Serum urate status, the prevalence of hyperuricemia and their relationship to the metabolic syndrome in elderly Taiwanese were described using data from the Elderly Nutrition and Health Survey in Taiwan (1999- 2000), in which a stratified multi-stage clustered sampling scheme was applied. Complete data from biochemical assays and anthropometric measures for 1225 males and 1167 females were included in the analysis. The mean urate level and 95% confidence interval was 411 (398, 424) μM for males and 357 (347, 367) μM for females. Males had significantly higher serum urate levels than females across all age groups (P <0. 05). No significant difference in mean serum urate was found among the four age groups of males. On the other hand, females of 75-79 years had significantly higher serum urate levels (376 μM) than that of the 65-69 and ≥ 80 age groups. The overall prevalence of hyperuricemia (≥ 416 .7 μM (7.0 mg/dL) in the elderly was 36% (46% for males and 26% for females). Among the participants, 4.2% of males and 1.1 % of females were taking medication to lower uric acid. The elderly (males 455 μM; females 416 μM ) of the Mountain areas, mainly indigenes, had the highest mean serum urate overall, however, the highest prevalence of hyperuricemia in males was found in the PengHu islands (62%) and that for females in the Mountain areas (51%). The odds ratio (OR) for hyperuricemia was 2.84 for males in the PengHu islands and 4.33 for females in Mountain areas, compared with their counterparts in the third stratum in the northern areas. Adjusting for obesity, alcohol and other related covariates did not alter the relative rank of the ORs in the various strata. Elderly males (22%) had a significantly lower rate of metabolic syndrome (MS) than females (39%) (P <0.05). For both genders, those with MS had a significantly higher mean serum urate (males 436 μM vs. 405 μM; females 389 μM...
|Appears in Collections:||醫學系|
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