https://scholars.lib.ntu.edu.tw/handle/123456789/202444
DC Field | Value | Language |
---|---|---|
dc.contributor | 檢驗醫學科 | en |
dc.contributor.author | LU, DANIEL C-T | en |
dc.contributor.author | CHUANG, YIN-CHING | en |
dc.contributor.author | LIU, YUNG-CHING | en |
dc.contributor.author | JANG, TSRANG-NENG | en |
dc.contributor.author | LU, PO-LIANG | en |
dc.contributor.author | CHEN, CHIH-MING | en |
dc.contributor.author | HSU, GWO-JONG | en |
dc.contributor.author | HSUEH, PO -REN | en |
dc.creator | 盧進德;莊銀清;劉永慶;張藏能;盧柏樑;陳志銘;許國忠;薛博仁 | zh-tw |
dc.creator | LU, DANIEL C-T;CHUANG, YIN-CHING;LIU, YUNG-CHING;JANG, TSRANG-NENG;LU, PO-LIANG;CHEN, CHIH-MING;HSU, GWO-JONG;HSUEH, PO -REN | en |
dc.date | 2008 | en |
dc.date.accessioned | 2009-12-24T07:52:15Z | - |
dc.date.accessioned | 2018-07-12T09:26:46Z | - |
dc.date.available | 2009-12-24T07:52:15Z | - |
dc.date.available | 2018-07-12T09:26:46Z | - |
dc.date.issued | 2008 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/175390 | - |
dc.description.abstract | Tigecycline In-vitro Surveillance in Taiwan (TIST), initiated in 2006, is a nationwide surveillance programme designed to monitor longitudinally the in-vitro activity of tigecycline against commonly encountered resistant bacteria. This study compared the in-vitro activity of tigecycline against clinical isolates of resistant Gram-negative bacteria determined by the broth microdilution and Etest methods. A total of 622 isolates were collected from patients treated at 20 teaching hospitals. Tigecycline had excellent in-vitro activity against extended-spectrum beta - lactamase (ESBL)-producing Escherichia coli (N = 275) with MIC90 0.5 mu g/mL and a 99.6% susceptibility rate, and also against ESBL-producing Klebsiella pneumoniae ( N = 324) with MIC90 2 mu g/mL and a 98.5% susceptibility rate. For ESBL- producing Proteus mirabilis (N = 15) the MIC90 was 4 mu g/mL with a 73.3% susceptibility rate. For ESBL-producing Klebsiella oxytoca (N = 8) the MIC50 and MIC90 were 0.5 and 1 mu g/mL, respectively, with a 100% susceptibility rate. Limited agreement (< 80%) was found between the broth microdilution and the Etest methods when determining the in- vitro activity of tigecycline against ESBL-producing K . pneumoniae and K. oxytoca. (C) 2008 Elsevier B. V. and the International Society of Chemotherapy. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS v.32 SUPPL. 3 pp.S179-S 183 | en |
dc.relation.ispartof | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
dc.subject | Tigecycline | en |
dc.subject | Extended-spectrum beta-lactamase | en |
dc.subject | Etest | en |
dc.subject | Broth microdilution | en |
dc.subject | Taiwan | en |
dc.subject | Enterobacteriaceae | en |
dc.title | Nationwide Surveillance in Taiwan of the in-Vitro Activity of Tigecycline against Clinical Isolates of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae | en |
dc.relation.pages | - | - |
dc.relation.journalvolume | v.32 | - |
dc.relation.journalissue | 183 | - |
item.languageiso639-1 | en_US | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
Appears in Collections: | 醫學系 |
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