https://scholars.lib.ntu.edu.tw/handle/123456789/202580
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 檢驗醫學科 | en |
dc.contributor.author | LEE, YUAN-TI | en |
dc.contributor.author | TSAUR, SHYH-MING | en |
dc.contributor.author | LEE, MENG-CHIH | en |
dc.contributor.author | HSUEH, PO-REN | en |
dc.creator | 李原地;曹世明;李孟智;薛博仁 | zh-tw |
dc.creator | LEE, YUAN-TI;TSAUR, SHYH-MING;LEE, MENG-CHIH;HSUEH, PO-REN | en |
dc.date | 2010 | en |
dc.date.accessioned | 2011-06-21T08:38:08Z | - |
dc.date.accessioned | 2018-07-12T09:33:07Z | - |
dc.date.available | 2011-06-21T08:38:08Z | - |
dc.date.available | 2018-07-12T09:33:07Z | - |
dc.date.issued | 2010 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/235656 | - |
dc.description.abstract | The present study investigated the long-term impact of antibiotic use policy on the rates of consumption (expressed as daily-defined doses/1000 patient-days) of various parenteral antibiotics and on the prevalence of methicillin- resistant Staphylococcus aureus (MRSA) and the incidence of healthcare-associated MRSA (HA-MRSA) infection at a tertiary care hospital from 2001 to 2009. During this time, consumption of all antimicrobials for systemic use decreased by 33%. This change was driven by a 44% decrease in the consumption of unrestricted antibacterials, which was offset by a 42% increase in the consumption of restricted agents. The trends in MRSA prevalence (number of isolates/1000 patient-days) and HA- MRSA incidence (number of HA-MRSA- infected persons/1000 patient-days) correlated with the trend in overall consumption of antimicrobials. Significant positive correlations were observed between MRSA prevalence and the consumption of extended-spectrum and beta-lactamase- resistant penicillins, first-generation cephalosporins, macrolides, lincosamides and streptogramins, aminoglycosides , and glycopeptides. Significant positive correlations were found between the incidence of HA-MRSA infection and the consumption of tetracyclines, extended-spectrum and beta- lactamase- resistant penicillins, sulfonamides and trimethoprim, macrolides, lincosamides and streptogramins, and aminoglycosides. In conclusion, we have documented the ongoing successful reduction in total consumption of antimicrobials associated with a decrease in the incidence of HA-MRSA and the prevalence of MRSA over a 9-year period. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS v.36 n.6 pp.523-530 | en |
dc.relation.ispartof | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
dc.subject | Antibiotic consumption | en |
dc.subject | Healthcare-associated infection | en |
dc.subject | Methicillin-resistant | en |
dc.subject | Staphylococcus aureus | en |
dc.subject | Correlation | en |
dc.subject | Taiwan | en |
dc.title | Decline in the Incidence of Healthcare-Associated Methicillin-Resistant Staphylococcus Aureus (Ha-Mrsa) Correlates with Deceased Antimicrobial Consumption at a Tertiary Care Hospital in Taiwan, 2001-2009 | en |
dc.relation.pages | 523-530 | - |
dc.relation.journalvolume | v.36 | - |
dc.relation.journalissue | n.6 | - |
item.languageiso639-1 | en_US | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
顯示於: | 醫學系 |
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