A Randomised Double-Blind Controlled Study Evaluating the Hypothermic Effect of 150 Microg Morphine during Spinal Anaesthesia for Caesarean Section
Resource
ANAESTHESIA v.61 n.1 pp.29-31
Journal
ANAESTHESIA
Journal Volume
v.61
Journal Issue
n.1
Pages
29-31
Date Issued
2006
Date
2006
Author(s)
HUI, CHUNG-KUN
LIN, CHEN-JUNG
LIU, HONG-PING
CHAN, WEI-HUNG
YEH, HUEI-MING
Abstract
We studied the hypothermic effect of adding 150 microg morphine during spinal anaesthesia in 60 parturients scheduled for elective caesarean section. All the parturients received intrathecal injection of a solution containing 150 mug morphine or normal saline in addition to 10-12 mg hyperbaric bupivacaine 0.5%. In both groups, a significant decrease in body temperature was noted. There was no difference in the area under the curve for temperature against time for the two groups; however, the maximum decrease in temperature from baseline was significantly larger after morphine than after saline injection (mean (SD) 1.11 (0.61) degrees C vs 0.76 (0.39) degrees C, respectively; p = 0.01) and the time to nadir temperature was significantly longer (59.5 (17.6) min vs 50. 4 (15.9) min, respectively; p = 0.047). The lowest temperature observed in the morphine group was 34.3 degrees C. We conclude that intrathecal injection of 150 microg morphine intensified the intra-operative hypothermic effect of bupivacaine spinal anaesthesia for caesarean section.
Subjects
SUBARACHNOID MORPHINE
Analgesics, Opioid/adverse effects
Anesthesia, Obstetrical/ adverse effects/methods
Anesthesia, Spinal/ adverse effects/methods
Anesthetics, Local/ adverse effects
Area Under Curve