|Title:||A Randomised Double-Blind Controlled Study Evaluating the Hypothermic Effect of 150 Microg Morphine during Spinal Anaesthesia for Caesarean Section||Authors:||HUI, CHUNG-KUN
|Keywords:||SUBARACHNOID MORPHINE;Analgesics, Opioid/adverse effects;Anesthesia, Obstetrical/ adverse effects/methods;Anesthesia, Spinal/ adverse effects/methods;Anesthetics, Local/ adverse effects;Area Under Curve||Issue Date:||2006||Journal Volume:||v.61||Journal Issue:||n.1||Start page/Pages:||29-31||Source:||ANAESTHESIA||Abstract:||
We studied the hypothermic effect of adding 150 microg morphine during spinal anaesthesia in 60 parturients scheduled for elective caesarean section. All the parturients received intrathecal injection of a solution containing 150 mug morphine or normal saline in addition to 10-12 mg hyperbaric bupivacaine 0.5%. In both groups, a significant decrease in body temperature was noted. There was no difference in the area under the curve for temperature against time for the two groups; however, the maximum decrease in temperature from baseline was significantly larger after morphine than after saline injection (mean (SD) 1.11 (0.61) degrees C vs 0.76 (0.39) degrees C, respectively; p = 0.01) and the time to nadir temperature was significantly longer (59.5 (17.6) min vs 50. 4 (15.9) min, respectively; p = 0.047). The lowest temperature observed in the morphine group was 34.3 degrees C. We conclude that intrathecal injection of 150 microg morphine intensified the intra-operative hypothermic effect of bupivacaine spinal anaesthesia for caesarean section.
|Appears in Collections:||醫學系|
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