DC 欄位 | 值 | 語言 |
dc.contributor | 國立臺灣大學醫學院復健科 | zh_TW |
dc.contributor.author | 王顏和 | zh_TW |
dc.creator | 王顏和 | zh_TW |
dc.date | 2005-07-31 | - |
dc.date.accessioned | 2006-07-26T05:44:36Z | - |
dc.date.accessioned | 2018-07-13T08:32:31Z | - |
dc.date.available | 2006-07-26T05:44:36Z | - |
dc.date.available | 2018-07-13T08:32:31Z | - |
dc.date.issued | 2005-07-31 | - |
dc.identifier | 932314B002119 | zh_TW |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/28987 | - |
dc.description.abstract | 目的:欲瞭解男性脊髓損傷患者與心
臟血管疾病危險因子之相關性,並評
估其頸動脈硬化的決定因子。
材料與方法: 87 位脊髓損傷的男性病
人參與本研究。每位病人先接受隔夜
空腹十小時的血液檢查,再進行75 克
的口服葡萄糖耐受性測試,及頸動脈
硬化檢查。檢查用的HP4500 SONOS
頸動脈超音波,配備3-10MHz 的高顯
像的即時M-mode,及3.6MHz 的杜卜勒
的探頭。基本的血脂值、血清發炎指
標和葡萄糖耐量試驗所測血中葡萄糖
值、胰島素及相關因子,則用來與頸
動脈內中皮層厚度做相關的分析。
結果:空腹2 小時的曲線下血糖值與
葡萄糖面積值皆是總頸動脈內中皮層
厚度重要的決定因子。混合迴歸分析
年齡及身體質量比皆是重要的頸動脈
內中皮層的決定因子。血壓值,無論
是收縮壓或舒張壓,皆不是頸動脈內
中皮層厚度的決定因子。
結論:除了身體質量比外,75 克葡萄
糖耐量試驗發現血中葡萄糖值,無論
是空腹或糖水負荷後,皆是總頸動脈
內中皮層厚度重要的決定因子。為了
預防心血管疾病,應鼓勵脊髓損傷病
人,多運動及預防過重。 | zh_TW |
dc.description.abstract | Aim: To identify the associated risk
factors for cardiovascular disease in
male patients with spinal cord injury
(SCI) and to study their determinants of
carotid atherosclerosis.
Material and Methods: Eighty-seven
male patients with traumatic SCI were
recruited. After overnight fasting for 10
hours, baseline venous blood sample
was obtained and then a 75-g oral
glucose tolerance test (OGTT) was
performed for each patient. HP 4500
SONOS carotid ultrasound equipped
with 3-10 MHz high-resolution real-time
M-mode and 3.6 MHz Doppler was also
performed for each patient. Baseline
lipid profile, serum inflammatory
marker (hs-CRP) and blood glucose and
insulin levels before and after OGTT
were used to evaluate the associations
with carotid intima-media thickness
(IMT) in different segments of common
carotid arteries (CCA). Multivariate
regression analysis with mixed models
was used to evaluate the associated
determinants of CCA IMT.
Results: Post-load 2-h glucose levels
and glucose area under curve after
OGTT were found as important
determinants for CCA IMT in different
segments. In addition to age, body mass
index (BMI) also was identified as
important determinant for carotid IMT.
However, office systolic and diastolic
blood pressures were not significant
predictor for CCA IMT.
Conclusion: OGTT identified glucose
level at 120 minutes and BMI are two
most important determinants for carotid
atherosclerosis in male SCI patients. To
2
prevent cardiovascular disease in SCI
subjects, exercise and weight control
should be emphasized. | en |
dc.format | application/pdf | zh_TW |
dc.format.extent | 134637 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.language | zh-TW | zh_TW |
dc.language.iso | zh_TW | - |
dc.publisher | 臺北市:國立臺灣大學醫學院復健科 | zh_TW |
dc.rights | 國立臺灣大學醫學院復健科 | zh_TW |
dc.subject | 脊髓損傷 | zh_TW |
dc.subject | 頸動脈內中皮層厚度 | zh_TW |
dc.subject | 口服葡萄糖耐受性測試 | zh_TW |
dc.subject | Spinal cord injury | en |
dc.subject | carotid intima-media-thickness | en |
dc.subject | oral glucose tolerance test | en |
dc.subject.classification | [SDGs]SDG3 | - |
dc.title | 男性脊髓損傷患者冠狀動脈心臟病危險因子之研究 | zh_TW |
dc.title | The study of risk factors for coronary heart disease in
men with spinal cord injury | en |
dc.type | other | en |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/28987/1/932314B002119.pdf | - |
dc.coverage | 計畫年度:93;起迄日期:2004-08-01/2005-07-31 | zh_TW |
item.openairetype | other | - |
item.fulltext | with fulltext | - |
item.languageiso639-1 | zh_TW | - |
item.cerifentitytype | Products | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_1843 | - |
顯示於: | 醫學系
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