https://scholars.lib.ntu.edu.tw/handle/123456789/292071
標題: | A peritoneal mesothelioma in a captive aardwolf (Proteles cristatus). | 作者: | PEN-HENG CHANG | 公開日期: | 2001 | 卷: | 25 | 期: | 3 | 起(迄)頁: | 193-196 | 來源出版物: | Proceedings of the National Science Council, Republic of China. Part B, Life sciences | 摘要: | A 10-year-old male aardwolf (Proteles cristatus) was presented abdominal distention and emaciation for 3 months. Physical examination revealed firm abdominal masses with effusions. Cytologic assessment of the effusion showed uniform round tumor cells with a surface brush border. Necropsy showed white velvety masses covering the peritoneal surface of the liver, gall bladder, stomach, omentum, mesentery, spleen, intestine, abdominal wall and diaphragm. Histologic examination demonstrated papillary projections, lined with cuboidal tumor cells supported by fibrous connective tissue cores, arising from the serosa of visceral organs. Cytoplasmic vacuolation and a surface brush border were evident on some cells under light microscopy. Tumor cells stained positive for both cytokeratin (AE1/AE3) and vimentin. Electron microscopy showed prominent surface microvilli, rough endoplasmic reticulum, mitochondria and desmosomes in tumor cells. This may be the first reported case of peritoneal mesothelioma in a captive wild aardwolf. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-0035405984&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/292071 |
SDG/關鍵字: | keratin; tumor marker; tumor protein; vimentin; animal; animal disease; article; ascites; cancer stem cell; Carnivora; case report; chemistry; male; mesothelioma; pathology; peritoneum tumor; ultrastructure; zoo animal; Animals; Animals, Zoo; Ascites; Carnivora; Keratins; Male; Mesothelioma; Neoplasm Proteins; Peritoneal Neoplasms; Tumor Markers, Biological; Tumor Stem Cells; Vimentin |
顯示於: | 分子暨比較病理生物學研究所 |
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