https://scholars.lib.ntu.edu.tw/handle/123456789/293963
標題: | Efficacy of a mass hepatitis B immunization program after switching to recombinant hepatitis B vaccine: A population-based study in Taiwan | 作者: | Hsu H.-M. Lee S.-C. Wang M.-C. Lin S.-F. DING-SHINN CHEN |
關鍵字: | Efficacy; Mass immunization; Recombinant hepatitis B vaccine | 公開日期: | 2001 | 卷: | 19 | 期: | 20-22 | 起(迄)頁: | 2825-2829 | 來源出版物: | Vaccine | 摘要: | To study the efficacy of immunization against hepatitis B after plasma-derived vaccine was replaced by recombinant vaccine, 2-year-old Taiwanese children were recruited by stratification random sampling and tested for hepatitis B markers. They were grouped according to maternal infectivity and children's immunization status. Of 2010 children, 2.5% had hepatitis B surface antigen (HBsAg), 94.1% had its antibody (anti-HBs), 6.8% had core antibody, and 3.3% were seronegative. Children of highly infectious mothers immunized with hepatitis B immunoglobulin and vaccine on schedule had a lower HBsAg-positive rate and a higher anti-HBs-positive rate than those with vaccine only and off-schedule. The efficacy of the Taiwanese mass hepatitis B immunization was maintained after switching to recombinant hepatitis B vaccine. ? 2001 Elsevier Science Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035815540&doi=10.1016%2fS0264-410X%2801%2900015-9&partnerID=40&md5=3aa3aa549ce838dc60caf107f2f76877 http://scholars.lib.ntu.edu.tw/handle/123456789/293963 |
DOI: | 10.1016/S0264-410X(01)00015-9 | SDG/關鍵字: | h b vax ii; hepatitis B antibody; hepatitis B core antibody; hepatitis B core antigen; hepatitis B surface antibody; hepatitis B surface antigen; hepatitis B vaccine; recombinant hepatitis B vaccine; article; blood sampling; controlled study; drug efficacy; female; hepatitis B; Hepatitis B virus; high risk population; human; infection prevention; intrauterine infection; major clinical study; male; plasma; preschool child; preventive health service; priority journal; serology; Taiwan; treatment outcome; Child, Preschool; Female; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Humans; Immunization; Immunoglobulins; Male; Taiwan; Vaccines, Synthetic |
顯示於: | 醫學系 |
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