https://scholars.lib.ntu.edu.tw/handle/123456789/314458
標題: | Morphological and functional types of neurons in cat ventral posterior thalamic nucleus | 作者: | Yen, C.-T. Conley, M. Jones, E.G. CHEN-TUNG YEN |
公開日期: | 1985 | 卷: | 5 | 期: | 5 | 起(迄)頁: | 1316-1338 | 來源出版物: | Journal of Neuroscience | 摘要: | Neurons in the thalamic ventral posterior (VB) nucleus of the cat were investigated by extracellular and intracellular recording and by anatomical methods involving either the retrograde transport of horseradish peroxidase (HRP) or the intracellular injection of HRP. Two morphological types of neurons could be detected by retrograde labeling from small injections of HRP in the internal capsule adjacent to VB. These two and one other type, judged to be an interneuron, could also be identified by intracellular staining. Type I cells are large, have thick proximal dendrites which branch in a tuft-like manner, and thick, rapidly conducting axons. They possess few or no dendritic appendages. Type II cells are smaller and have slender proximal dendrites which branch dichotomously and thin, slower conducting axons. Those injected intracellularly are covered in fine, hair-like dendritic appendages. Type III cells are small and have thin processes that give rise to many bulbous dilatations and no obvious axon. Type I and type II cells give off slender axon collaterals in the thalamic reticular nucleus but not in VB. Examples of both types of cell could be antidromically activated from the somatic sensory cortex. Type I and type II cells recovered histologically after intracellular recording included examples of most types of receptive field, including several forms of cutaneous and deep fields, as classified by us in a parallel intra- and extracellular study of unit responses. All but one type I cell, however, responded in a transient manner to peripheral stimulation. The remaining type I cell and all members of an admittedly small sample of type II cells responded in a sustained manner. The sample of recovered interneurons and of units that could not be driven antidromically from the cerebral cortex suggested that they, too, included all receptive field types. We conclude that submodality specificity in VB is not represented by morphological specificity in thalamocortical relay cells or interneurons. Some other functional parameter, such as tonic or phasic responsiveness, may be more obviously correlated with relay cell morphology. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-0021983588&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/314458 https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021983588&doi=10.1523%2fjneurosci.05-05-01316.1985&partnerID=40&md5=af0c75ab765f7eafce86f2b1f0f492ed |
ISSN: | 02706474 | SDG/關鍵字: | horseradish peroxidase; animal cell; cat; cell shape; central nervous system; cytology; electron microscopy; histology; nerve fiber; nervous system; nonhuman; preliminary communication; priority journal; thalamocortical tract; thalamus nucleus |
顯示於: | 生命科學系 |
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