A convenient synthesis of propargylic dithioacetals
Journal
Synlett
Journal Issue
18
Pages
3173-3175
Date Issued
2006
Author(s)
Abstract
Treatment of trimethylsilyl-substituted alkynyl ketones with 1,2-ethanedithiol in the presence of BF3·OEt2 in methanol afforded the corresponding dithioacetal. Removal of the silyl group under basic conditions followed by palladium-catalyzed coupling reactions with aryl iodides yielded the corresponding propargylic dithioacetals in excellent yield.
SDGs
Type
journal article