|Title:||Determinants of adherence to methylphenidate and the impact of poor adherence on maternal and family measures||Authors:||SUSAN SHUR-FEN GAU||Issue Date:||2006||Journal Volume:||16||Journal Issue:||3||Start page/Pages:||286-297||Source:||Journal of Child and Adolescent Psychopharmacology||Abstract:||
Objective: The aim of this study was to examine the association between adherence to immediate-release methylphenidate (IR MPH) and maternal psychological distress, parenting style, parent-child relationship, and perceived family support. Methods: The sample consisted of 307 children with attention-deficit hyperactivity disorder (ADHD) (271 boys and 36 girls), 6-17 years of age, who had been treated with IR MPH for the past 6 months. The measures included the Chinese Health Questionnaire, Parental Bonding Instrument, Family APGAR, and Home Behaviors of the Social Adjustment Inventory for Children and Adolescents. Results: Reasons for poor adherence (n = 79; 25.7%) included forgetting medication (72.7%), the medication having no effect (20.0%), and refusing medication (12.7%). Increased age and three-times-daily administration were the major predictors for poor adherence to IR MPH. Poor adherence was associated with increased degree of maternal psychological distress, indifferent parenting, maternal overprotection/control, poor family support, decreased interaction with parents, and increased problems at home. Conclusions: Findings indicate that multiple daily dosing of MPH increases the likelihood of poor adherence, particularly in adolescents, and that poor adherence is associated with impaired maternal/family process. Once-daily administration of MPH is necessary to improve adherence and to decrease the possible exacerbation of tense parent-child relationships caused by poor drug adherence.
|DOI:||10.1089/cap.2006.16.286||metadata.dc.subject.other:||methylphenidate; adolescent; age; article; attention deficit disorder; child; child care; child parent relation; Chinese health questionnaire; drug efficacy; Family APGAR; family life; female; follow up; Home Behaviors of Social Adjustment Inventory for children and adolescents; human; major clinical study; male; parental bonding instrument; patient compliance; prediction; psychological aspect; questionnaire; rating scale; social support; Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Drug Administration Schedule; Female; Humans; Male; Methylphenidate; Parent-Child Relations; Patient Compliance; Taiwan
|Appears in Collections:||醫學系|
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