https://scholars.lib.ntu.edu.tw/handle/123456789/325965
標題: | Effect of a vegetarian diets on the vitamin B status and homocysteine levels in elderly Taiwanese | 作者: | Chen, K.-J. Shaw, N.-S. Pan, W.-H. Feili, L.Y. Lin, B.-F. BI-FONG LIN |
關鍵字: | Folate; Homocysteine; Vegetarians; Vitamin B12 | 公開日期: | 2006 | 卷: | 31 | 期: | 4 | 起(迄)頁: | 117-126 | 來源出版物: | Nutritional Sciences Journal | 摘要: | To investigate the effects of a vegetarian diets on the vitamin B status and homocysteine (Hcy) levels in elderly Taiwanese, we analyzed plasma folate and Hcy levels in 47 vegetarians, 314 occasional vegetarians and 1056 non-vegetarians aged ? 65 years, sampled from the Elderly Nutrition and Health Survey in Taiwan (1999-2000) (Elderly NAHSIT). Results showed that the average plasma Hcy levels of vegetarians (14.3 ± 0.6 μmol/L) were significantly higher than those of occasional vegetarians (12.5 ± 0.3 μmol/L) and non-vegetarians (12.3 ± 0.1 μmol/L). The vegetarians had significantly higher levels of plasma folate (13.1 ± 0.8 ng/mL) than the occasional vegetarians (11.1 ± 0.3 ng/mL) and non-vegetarians (11.4 ± 0.2 ng/mL), and a better vitamin B2 status assessed by the levels of the erythrocyte glutathione reductase activity coefficient (EGRAC, 1.00 ± 0.02), but lower levels of serum vitamin B12 (381 ± 36 pmol/L). There were significantly higher prevalences of vitamin B12 insufficiency and hyperhomocysteinemia (Hcy > 15 μmol/L), but lower prevalences of vitamin B2 or B6 insufficiency in the vegetarians group than those in occasional vegetarians and non-vegetarians groups. After adjusting for several effect factors, the plasma Hcy levels in the elderly with a vitamin B12 insufficiency were significantly higher in vegetarians than those in occasional vegetarians and non-vegetarians, but in those with folate, vitamin B2 or B6 insufficiency did not significantly differ among the three diet groups. Therefore, maintaining a good vitamin B12 status should be emphasized for vegetarian subjects to avoid elevated Hcy levels. In addition, occasional vegetarians had the lowest prevalences of hyperhomocysteinemia and lower prevalences of vitamin B 2 or B12 insufficiency compared to non-vegetarians, suggesting that further study may be worth while to investigate whether an occasional vegetarian diet is more beneficial for the elderly. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-34247613190&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/325965 |
SDG/關鍵字: | cyanocobalamin; folic acid; homocysteine; vitamin B group; amino acid blood level; article; controlled study; cyanocobalamin deficiency; folic acid blood level; human; hyperhomocysteinemia; prevalence; Taiwan; vegetarian diet; vitamin blood level |
顯示於: | 生化科技學系 |
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